Acebrophylline (200mg SR), Desloratadine (5mg), Montelukast (10mg) .. . . . .. .

Respiratory disorders, particularly those involving airway inflammation and allergic reactions, are increasingly common in India due to environmental pollution, seasonal allergens, smoking, and lifestyle factors. Conditions like asthma, chronic bronchitis, allergic rhinitis, and COPD can significantly impair breathing, sleep quality, and daily functioning. Managing these conditions effectively requires medications that target multiple pathways, including bronchoconstriction, mucus accumulation, and allergic inflammation.

S PHYLLIN DM is a scientifically formulated combination medicine containing Acebrophylline 200 mg SR (sustained-release), Desloratadine 5 mg, and Montelukast 10 mg. This unique triple combination offers a multi-dimensional approach to respiratory care: it relaxes the airways, reduces mucus, controls allergic reactions, and prevents long-term complications.

Acebrophylline acts as a bronchodilator and mucolytic, improving airflow and making cough more productive. Desloratadine is a non-sedating antihistamine, reducing allergy symptoms such as sneezing, itching, and nasal congestion. Montelukast is a leukotriene receptor antagonist that helps prevent airway inflammation and bronchospasm triggered by allergens or exercise. Together, these ingredients offer comprehensive relief from chronic respiratory and allergic conditions, making S PHYLLIN DM a reliable choice under medical supervision.

Uses of S PHYLLIN DM

Acebrophylline tablet uses is used for the management of allergic respiratory conditions and obstructive airway diseases. It is especially beneficial for patients who require multi-mechanism therapy to improve breathing and reduce allergy symptoms.

Primary Uses

• Chronic bronchitis with cough and mucus production

• Asthma (allergic and chronic types)

• Chronic obstructive pulmonary disease (COPD)

• Allergic rhinitis and seasonal allergies

• Shortness of breath due to airway constriction

• Exercise-induced bronchospasm

• Prevention of recurrent asthma attacks

Mechanism of Action

• Acebrophylline 200 mg SR: Acts as a bronchodilator by relaxing airway smooth muscles and as a mucolytic to thin mucus, making it easier to expel.

• Desloratadine 5 mg: Blocks histamine receptors, reducing allergy symptoms such as sneezing, itching, runny nose, and watery eyes without causing drowsiness.

• Montelukast 10 mg: Blocks leukotriene receptors, preventing airway inflammation, bronchospasm, and mucus hypersecretion, thereby controlling asthma and allergic rhinitis.

This triple-action approach addresses bronchoconstriction, inflammation, and allergic reactions, providing effective symptomatic relief and long-term protection against flare-ups.

Benefits of S PHYLLIN DM

Tab acebrophylline offers several benefits for patients suffering from chronic respiratory and allergic conditions.

1. Effective Bronchodilation

Relieves airway constriction, improves airflow, and reduces shortness of breath.

2. Mucolytic Action

Acebrophylline helps thin thick mucus, making cough productive and improving lung clearance.

3. Allergy Control

Desloratadine reduces sneezing, nasal congestion, and itching without causing sedation.

4. Anti-inflammatory Protection

Montelukast prevents airway inflammation and bronchospasm, reducing asthma attacks and seasonal flare-ups.

5. Sustained Symptom Relief

The sustained-release formulation of Acebrophylline ensures long-lasting effect, reducing the need for frequent dosing.

6. Improves Quality of Life

Helps patients breathe easier, sleep better, and perform daily activities without discomfort.

7. Reduces Exacerbations

Effective in preventing recurrent asthma attacks and worsening of chronic bronchitis or COPD.

8. Safe for Long-Term Use

When prescribed and monitored by a healthcare professional, it is suitable for long-term therapy.

Dosage of S PHYLLIN DM

The dosage of acebrophylline sustained release tablets should be strictly followed according to the physician’s instructions, depending on the patient’s age, severity of symptoms, and overall health condition.

Recommended Dosage

• Adults and children above 12 years: 1 tablet once daily in the evening

• Swallow the tablet whole with water

• Can be taken with or without food

Administration Guidelines

• Do not crush, chew, or break the tablet

• Take at the same time every day for consistent therapeutic effect

• Continue therapy even if symptoms improve, unless advised otherwise

• Combination with lifestyle measures like avoiding allergens, quitting smoking, and maintaining proper hydration improves effectiveness

Missed Dose

• Take the missed dose as soon as remembered

• Skip it if it is close to the next scheduled dose

• Do not take a double dose

Side Effects of S PHYLLIN DM

While S PHYLLIN DM is generally well tolerated, some patients may experience side effects, especially during initial therapy.

Common Side Effects

• Headache

• Nausea or mild stomach upset

• Dizziness

• Dry mouth or throat

• Mild drowsiness (rare with Desloratadine)

Less Common Side Effects

• Palpitations

• Heartburn

• Mild fatigue

• Abdominal discomfort

Rare but Serious Side Effects

• Severe allergic reactions (rash, swelling, difficulty breathing)

• Liver enzyme elevation (rare, usually monitored in long-term therapy)

• Irregular heartbeat or chest discomfort

• Neuropsychiatric symptoms (rarely reported with Montelukast, e.g., agitation or sleep disturbances)

Patients experiencing any severe or persistent side effects should contact their healthcare provider immediately.

Warnings

• Use with caution in patients with liver or kidney impairment

• Not recommended for children below 12 years unless prescribed

• Monitor for any allergic reactions when using for the first time

• Montelukast may rarely cause mood changes; report any behavioral changes to your doctor

• Not a substitute for emergency asthma medication such as inhaled bronchodilators

Precautions

• Inform your doctor about existing medical conditions, especially liver, kidney, or heart disorders

• Avoid alcohol while taking S PHYLLIN DM, as it may worsen drowsiness or dizziness

• Maintain adequate hydration to support mucus clearance

• Do not self-adjust the dosage without medical advice

• Elderly patients may require closer monitoring due to comorbidities

• Keep out of reach of children

• Store in a cool, dry place away from direct sunlight

Conclusion

S PHYLLIN DM (Acebrophylline 200 mg SR + Desloratadine 5 mg + Montelukast 10 mg) is a comprehensive, multi-action therapy for chronic respiratory and allergic conditions. By combining bronchodilation, mucus clearance, allergy control, and anti-inflammatory protection, it provides long-lasting relief and reduces the frequency of exacerbations.

With its sustained-release formulation and triple-mechanism approach, S PHYLLIN DM helps patients breathe easier, sleep better, and improve their quality of life. When used responsibly under medical supervision, alongside lifestyle modifications and avoidance of triggers, it is an effective solution for long-term respiratory health.

Frequently Asked Questions (FAQs)

Q1. What is S PHYLLIN DM used for?

It is used to treat chronic bronchitis, asthma, allergic rhinitis, and COPD by reducing airway constriction, inflammation, and allergy symptoms.

Q2. Is S PHYLLIN DM a steroid?

No, it contains a bronchodilator (Acebrophylline), an antihistamine (Desloratadine), and a leukotriene receptor antagonist (Montelukast). It is not a steroid.

Q3. Can S PHYLLIN DM be used long term?

Yes, under medical supervision, it is suitable for long-term management of chronic respiratory and allergic conditions.

Q4. Will S PHYLLIN DM cause drowsiness?

Desloratadine is a non-sedating antihistamine, so drowsiness is rare. Some mild fatigue may occur in certain patients.

Q5. Can it be used in children?

It is generally prescribed for children above 12 years. Pediatric dosing should be strictly followed as per doctor’s instructions.