MESALMILE 500 PR Mesalamine DR (500mg):Uses, Side effect, Pictures and more...

Jul 18, 2024

MESALMILE 500 PR 

Mesalamine DR (500mg)

MESALMILE 500 PR, a delayed-release formulation of Mesalamine 500mg, is a widely used medication in the management of inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease. This article provides a comprehensive overview of MESALMILE 500 PR, including its uses, dosage, side effects, and other essential information.

What is Mesalamine?

Mesalamine, also known as 5-aminosalicylic acid (5-ASA), is an anti-inflammatory drug that targets the lining of the colon to reduce inflammation. It is particularly effective in treating mild to moderate ulcerative colitis and maintaining remission in Crohn's disease.

How MESALMILE 500 PR Works

MESALMILE 500 PR works by releasing Mesalamine directly into the colon, where it exerts its anti-inflammatory effects. The delayed-release formulation ensures that the active ingredient reaches the targeted area of inflammation, maximizing its therapeutic benefits while minimizing systemic side effects.

Uses of MESALMILE 500 PR

Treatment of Ulcerative Colitis

MESALMILE 500 PR is primarily used to treat active ulcerative colitis, reducing symptoms such as diarrhea, rectal bleeding, and abdominal pain. It helps achieve and maintain remission, improving the quality of life for patients.

Management of Crohn's Disease

Although less commonly used than in ulcerative colitis, MESALMILE 500 PR can be beneficial in managing Crohn's disease, particularly in mild to moderate cases. It helps reduce inflammation and prevent flare-ups.

Maintenance Therapy

MESALMILE 500 PR is effective as a maintenance therapy to prevent the recurrence of symptoms in both ulcerative colitis and Crohn's disease. Regular use can help keep the disease in remission.

Dosage and Administration

Recommended Dosage

The standard dosage of MESALMILE 500 PR for adults is 500mg taken three times daily, depending on the severity of the condition. The dosage may be adjusted by the healthcare provider based on the patient's response and clinical condition.

How to Take MESALMILE 500 PR

  • Oral Administration: MESALMILE 500 PR tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets, as this can affect the delayed-release mechanism.
  • With or Without Food: The medication can be taken with or without food. However, taking it with food may help reduce any potential stomach discomfort.

Side Effects of MESALMILE 500 PR

Like all medications, MESALMILE 500 PR can cause side effects, although not everyone experiences them. It is important to be aware of potential side effects and consult a healthcare provider if they occur.

Common Side Effects

  • Nausea: Mild nausea may occur, particularly when starting the medication.
  • Headache: Some patients may experience headaches.
  • Diarrhea: Although it treats diarrhea in ulcerative colitis, MESALMILE 500 PR can occasionally cause it as a side effect.

Serious Side Effects

  • Kidney Problems: Rarely, Mesalamine can cause kidney issues. 
  • Allergic Reactions: Severe allergic reactions, including rash, itching, swelling, and difficulty breathing, require immediate medical attention.
  • Liver Issues: Liver function should be monitored during long-term use.

Precautions and Warnings

Before Taking MESALMILE 500 PR

  • Medical History: Discuss your medical history, especially if you have kidney or liver problems, with your doctor.

During Treatment

  • Regular Monitoring: Periodic blood tests may be required to monitor kidney and liver function.
  • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as Mesalamine can pass into breast milk.

Drug Interactions

MESALMILE 500 PR may interact with other medications, potentially altering their effects. 

Notable Interactions

  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Concurrent use with NSAIDs may increase the risk of kidney problems.
  • Anticoagulants: There is a potential risk of increased bleeding when used with anticoagulants.

Conclusion

MESALMILE 500 PR is a valuable medication in the management of inflammatory bowel diseases, offering relief from symptoms and helping maintain remission. Its delayed-release formulation ensures targeted delivery of Mesalamine, enhancing its efficacy. Always follow your healthcare provider's instructions regarding dosage and administration, and report any side effects promptly. With proper use, MESALMILE 500 PR can significantly improve the quality of life for individuals with ulcerative colitis and Crohn's disease.For more detailed information and personalized advice, consult your healthcare provider. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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