Methimazole

Nov 26, 2022

Introduction

METHIMZOLE 5 is a widely used antithyroid medication containing Methimazole (5mg). It is primarily prescribed for the treatment of hyperthyroidism, a condition in which the thyroid gland produces excessive thyroid hormones. By inhibiting the production of these hormones, METHIMZOLE 5 helps regulate thyroid function, alleviating symptoms such as rapid heartbeat, weight loss, nervousness, and excessive sweating. This medication plays a crucial role in managing conditions like Graves’ disease and is often used before thyroid surgery or radioactive iodine therapy.

Key Ingredient

Methimazole (5mg)

  • Methimazole belongs to the thionamide class of drugs, specifically designed to inhibit thyroid hormone synthesis.

  • It blocks the enzyme thyroid peroxidase, which is essential for the production of thyroxine (T4) and triiodothyronine (T3).

  • By reducing excessive thyroid hormone levels, Methimazole helps restore normal metabolism and overall health.

Uses of METHIMZOLE 5

  • Treatment of hyperthyroidism caused by an overactive thyroid gland.

  • Management of Graves' disease, an autoimmune disorder leading to excessive thyroid hormone production.

  • Preoperative preparation before thyroid surgery to reduce thyroid hormone levels.

  • Adjunct therapy before radioactive iodine treatment to stabilize thyroid hormone secretion.

  • Prevention of thyroid storm, a life-threatening complication of untreated hyperthyroidism.

Key Benefits

  • Effectively controls overactive thyroid function by reducing hormone production.

  • Alleviates symptoms such as palpitations, anxiety, tremors, and heat intolerance.

  • Reduces the risk of thyroid complications, including heart-related issues.

  • Helps in the long-term management of Graves’ disease.

  • Improves quality of life by restoring hormonal balance.

How Does METHIMZOLE 5 Work?

  • Methimazole (5mg) works by inhibiting the enzyme thyroid peroxidase, which plays a key role in thyroid hormone synthesis.

  • It prevents the incorporation of iodine into tyrosine residues, a crucial step in forming T3 and T4 hormones.

  • Over time, the reduced hormone levels help normalize metabolic functions, improving symptoms associated with hyperthyroidism.

  • Unlike radioactive iodine therapy or thyroidectomy, METHIMZOLE 5 offers a non-invasive approach to controlling hyperthyroidism.

Dosage and Administration

  • The dosage of METHIMZOLE 5 depends on the severity of hyperthyroidism, age, and response to treatment.

  • Typically, the starting dose is 5-15 mg per day, divided into multiple doses if necessary.

  • Once thyroid hormone levels are under control, the maintenance dose is usually 5-10 mg daily.

  • Take the medication with or without food, but preferably at the same time each day.

  • Regular blood tests may be required to monitor thyroid function and dosage adjustments.

  • Always follow your doctor’s prescription and do not stop the medication abruptly.

Side Effects of Methimazole (5mg)

While METHIMZOLE 5 is generally well-tolerated, some individuals may experience side effects, including:

Common Side Effects

  • Nausea or vomiting

  • Dizziness or drowsiness

  • Altered taste sensation

  • Mild rash or itching

Serious Side Effects (Rare Cases)

  • Agranulocytosis (a severe drop in white blood cells, leading to increased infection risk)

  • Liver toxicity (manifesting as jaundice, dark urine, or abdominal pain)

  • Joint pain or swelling

  • Severe allergic reactions (swelling, difficulty breathing, or skin reactions)

If any serious side effects occur, seek immediate medical attention.

Precautions and Warnings

  • Pregnant and breastfeeding women should consult a doctor, as Methimazole can cross the placenta and enter breast milk.

  • Individuals with liver disease, blood disorders, or compromised immunity should use METHIMZOLE 5 with caution.

  • Avoid high-iodine foods like seaweed, iodized salt, and shellfish, as they may interfere with the medication's effectiveness.

  • Do not stop taking the medication abruptly, as it may lead to a sudden worsening of hyperthyroidism.

  • Regular thyroid function tests are crucial for monitoring the treatment’s progress.

Drug Interactions

  • Beta-blockers (e.g., propranolol) may be used alongside Methimazole to manage symptoms like rapid heartbeat.

  • Anticoagulants (e.g., warfarin) may require dosage adjustments, as Methimazole affects blood clotting.

  • Theophylline (used for asthma) may have altered metabolism when taken with Methimazole.

  • Always inform your doctor about other medications, supplements, or herbal products before starting METHIMZOLE 5.

Price of METHIMZOLE 5 (Methimazole 5mg)

The price of METHIMZOLE 5 varies depending on factors such as brand, location, and pharmacy. Generally, the cost ranges from ₹50 to ₹200 per strip (containing 10 or more tablets). It is available in local pharmacies and online drugstores. Discounts and insurance coverage may further impact the final cost.

FAQs

1. How long does it take for METHIMZOLE 5 to show results?

It typically takes several weeks to months for noticeable improvement in hyperthyroid symptoms.

2. Can I take METHIMZOLE 5 long-term?

Yes, but long-term use requires careful monitoring of thyroid function and possible side effects.

3. Is it safe to take METHIMZOLE 5 during pregnancy?

Consult a doctor, as Methimazole may pose risks to the developing fetus, especially in the first trimester.

4. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it’s near the time for the next dose, skip the missed dose and continue as scheduled. Do not double the dose.

5. Can I stop taking METHIMZOLE 5 once my symptoms improve?

No, stopping suddenly can cause thyroid hormone levels to spike. Always consult your doctor before discontinuing.

Conclusion

METHIMZOLE 5 containing Methimazole (5mg) is a highly effective treatment for hyperthyroidism. It works by inhibiting thyroid hormone production, helping restore hormonal balance and alleviate symptoms. Regular use under medical supervision ensures effective thyroid management and prevents complications. If you have been diagnosed with hyperthyroidism, consult your doctor to determine if METHIMZOLE 5 is the right treatment for you.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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