Methotrexate (2.5 mg)

Introduction

METROTREX 2.5 is a trusted and clinically approved disease-modifying antirheumatic drug (DMARD) containing Methotrexate 2.5mg. Widely prescribed for rheumatoid arthritis, psoriasis, and various cancers, Methotrexate works by inhibiting DNA synthesis, suppressing the immune system, and slowing down cell division.

Key Features & Composition

• Brand Name: METROTREX 2.5

• Active Ingredient: Methotrexate 2.5mg

• Drug Class: Antimetabolite, DMARD, Immunosuppressant

• Form: Oral Tablet

Therapeutic Uses

Rheumatoid Arthritis (RA)

Slows joint damage and progression of inflammation

Psoriasis and Psoriatic Arthritis

Reduces skin scaling, redness, and joint pain

Certain Cancers

Used in the treatment of:

• Leukemia (ALL)

• Breast Cancer

• Lung Cancer

• Lymphoma

• Choriocarcinoma

Ectopic Pregnancy (low-dose usage)

Helps medically resolve non-viable pregnancies

How METROTREX 2.5 Works

Methotrexate inhibits the enzyme dihydrofolate reductase (DHFR), leading to a reduction in DNA synthesis and cell division, especially in rapidly dividing cells such as:

• Cancer cells

• Immune system cells

• Skin cells (in psoriasis)

This mechanism makes it effective in autoimmune suppression and tumor growth inhibition.

Benefits of METROTREX 2.5

• Slows disease progression in autoimmune conditions

• Reduces joint pain, swelling, and skin lesions

• Effective in low-dose weekly treatment plans

• Oral tablet form for easy administration

• Backed by decades of clinical use and research

• Cost-effective treatment for chronic conditions

Dosage and Administration

• For rheumatoid arthritis or psoriasis: Usually once a week, not daily.

• For cancer therapy: As prescribed by oncologist—may vary from daily to weekly depending on protocol.

Precautions and Warnings

• Avoid during pregnancy – Methotrexate is highly teratogenic

• Regular liver and kidney function monitoring is essential

• Avoid alcohol consumption

• Supplement folic acid as advised to reduce side effects

• Inform your doctor about all medications or supplements you're taking

Possible Side Effects

Common:

• Nausea or vomiting

• Mouth ulcers

• Fatigue

• Hair thinning

• Diarrhea

Serious:

• Liver damage

• Bone marrow suppression

• Lung toxicity (pneumonitis)

• Kidney impairment

Storage Instructions

• Store in a cool, dry place below 25°C

• Protect from light and moisture

• Keep out of reach of children

FAQs – METROTREX 2.5

Q1. What is METROTREX 2.5 used for?

It is mainly used for rheumatoid arthritis, psoriasis, and certain types of cancer.

Q2. How often should I take Methotrexate 2.5mg?

Usually once a week, but always follow your doctor’s prescription.

Q3. Is Methotrexate a chemotherapy drug?

Yes, at higher doses it is used in cancer chemotherapy, while at lower doses it acts as an immunosuppressant.

Q4. Can I take folic acid with Methotrexate?

Yes, it is often prescribed to reduce side effects such as mouth ulcers and liver strain.

Q5. Is long-term use of METROTREX 2.5 safe?

Yes, under regular medical supervision and routine lab tests, long-term use is safe for many patients.

Conclusion

METROTREX 2.5 (Methotrexate 2.5mg) is a powerful and versatile medication, trusted for over 60 years in managing autoimmune diseases and cancers. With correct dosing, monitoring, and medical supervision, it helps patients lead better, pain-free, and productive lives. Always consult your physician for personalized guidance.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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