Mirabegron 50mg & Solifenacin 5mg (Miragron S 50/5): Uses & Dosage

MIRAGRON S 50/5 

Mirabegron (ER) (50mg) and Solifenacin succinate (5mg)

Introduction

Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg), marketed under the brand name "Miragron S 50/5," is a combination medication used to treat overactive bladder (OAB). This article provides a comprehensive overview of this combination therapy, including its uses, dosage, side effects, price, and concluding thoughts.

Uses of Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg)

Treatment of Overactive Bladder (OAB)

Miragron S 50/5 is primarily prescribed for the treatment of overactive bladder (OAB) in adults. OAB is characterized by symptoms such as frequent urination, urgent need to urinate, and urinary incontinence. This combination therapy offers a dual mechanism of action to provide enhanced symptom control.

Dual Mechanism of Action

• Mirabegron (ER) (50mg): Mirabegron is a beta-3 adrenergic agonist that works by relaxing the detrusor muscle in the bladder, thereby increasing bladder capacity and reducing the urgency and frequency of urination.
• Solifenacin Succinate (5mg): Solifenacin is an antimuscarinic agent that helps reduce bladder muscle spasms, further aiding in the management of urinary urgency and frequency.

Dosage and Administration

Standard Dosage

The typical starting dose of Miragron S 50/5 for adults is one tablet once daily. The extended-release formulation ensures a steady release of medication throughout the day, providing consistent symptom relief.

How to Take

Miragron S 50/5 should be taken orally, once daily, with or without food. It is important to swallow the extended-release tablet whole with water and not to crush, chew, or divide the tablet, as this can affect the medication's efficacy.

Consequences of Solifenacin Succinate (5 mg) with Mirabegron (ER) (50 mg)

Common Side Effects

• Dry Mouth: Solifenacin Succinate can cause dry mouth, which may be alleviated by drinking plenty of fluids and using sugar-free gum or candy.
• Constipation: Patients may experience constipation, a common side effect of antimuscarinic agents.
• Headache: Some patients may experience headaches, generally mild and temporary.
• Increased Blood Pressure: Mirabegron can cause an increase in blood pressure. Regular monitoring is recommended, especially for patients with pre-existing hypertension.

Serious Side Effects

• Allergic Reactions: Rarely, severe allergic reactions such as rash, itching, swelling, severe dizziness, or trouble breathing can occur. 
• Heart Palpitations: In some cases, patients may experience heart palpitations or an irregular heartbeat. Consult your doctor if you experience any unusual heart-related symptoms.
• Severe Constipation: Severe constipation can occur, requiring medical intervention.

Price of Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg)

The cost of Miragron S 50/5 varies depending on the brand, location, and pharmacy. On average, a month's supply of this combination therapy may range from $150 to $250. Some insurance plans may cover part or all of the cost, and generic versions may offer a more affordable option.

Conclusion

Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg), marketed as Miragron S 50/5, is a highly effective combination therapy for managing an overactive bladder. The dual mechanism of action offers enhanced symptom control, making it a preferred choice for patients with more severe OAB symptoms. While generally well-tolerated, it is essential to be aware of potential side effects and adhere to the prescribed dosage. Regular consultation with a healthcare provider can ensure the medication's efficacy and safety. As with any medication, discussing any concerns or symptoms with a healthcare professional is crucial for achieving the best therapeutic outcomes. Miragron S 50/5 provides significant relief for those suffering from OAB, improving their quality of life and daily functioning. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

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