Naproxen (250mg), Domperidone SR(30mg) & NAPROXZEN D 250: Sterispharma….

May 22, 2024

Naproxen (250mg), Domperidone SR(30mg) & NAPROXZEN D 250

Naproxen (250mg) and Domperidone SR (30mg). This unique combination offers a synergistic approach to managing various conditions, providing relief from pain and addressing gastrointestinal issues simultaneously. In this comprehensive guide, we delve into the composition, mechanism of action, therapeutic uses, dosage, side effects, precautions, and interactions of Naproxen D 250, offering valuable insights for both patients and healthcare professionals.

Composition:

Naproxen D 250 contains two active ingredients: Naproxen and Domperidone SR. Naproxen belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs), known for its analgesic, anti-inflammatory, and antipyretic properties. Domperidone SR is a dopamine antagonist primarily used to alleviate symptoms of nausea and vomiting by enhancing gastrointestinal motility. The combination of these two medications in Naproxen D 250 offers a comprehensive approach to managing pain and gastrointestinal discomfort.

Mechanism of Action:

Naproxen exerts its therapeutic effects by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the production of prostaglandins responsible for inflammation, pain, and fever. Domperidone SR acts as a peripheral dopamine receptor antagonist, exerting antiemetic effects by enhancing gastric emptying and intestinal motility. Together, these mechanisms help alleviate pain and gastrointestinal symptoms, providing relief to patients with various conditions.

Therapeutic Uses:

Naproxen D 250 is indicated for the management of various conditions, including:

  1. Pain relief: Naproxen D 250 is effective in relieving mild to moderate pain associated with conditions such as headache, migraine, dental pain, menstrual cramps, and musculoskeletal disorders.
  2. Anti-inflammatory effects: The anti-inflammatory properties of Naproxen help reduce inflammation associated with conditions like arthritis, osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
  3. Gastrointestinal symptoms: Domperidone SR component of Naproxen D 250 provides relief from nausea, vomiting, bloating, and other gastrointestinal discomfort.
  4. Dysmenorrhea: Naproxen D 250 is commonly prescribed for the management of primary dysmenorrhea, offering pain relief during menstruation.

Dosage and Administration:

The recommended dosage of Naproxen D 250 may vary depending on the patient's age, weight, and the severity of the condition being treated. It is typically administered orally, preferably with food to minimize gastrointestinal side effects. Patients should follow the dosage instructions provided by their healthcare provider and avoid exceeding the prescribed dose to prevent adverse effects. 

Side Effects:

Like any medication, Naproxen D 250 may cause side effects in some individuals. Common side effects associated with Naproxen include gastrointestinal disturbances such as abdominal pain, indigestion, nausea, and diarrhea. Domperidone SR may cause dry mouth, headache, dizziness, and changes in heart rate. Serious side effects such as gastrointestinal bleeding, allergic reactions, and cardiovascular events are rare but may occur in susceptible individuals. 

Precautions and Warnings:

Before taking Naproxen D 250, patients should inform their healthcare provider about any existing medical conditions, allergies, or medications they are currently taking, including over-the-counter and herbal supplements. Individuals with a history of gastrointestinal ulcers, bleeding disorders, cardiovascular disease, renal impairment, or liver dysfunction should use Naproxen D 250 with caution under medical supervision. Long-term use of NSAIDs like Naproxen may increase the risk of adverse effects, including gastrointestinal ulcers and cardiovascular events. Pregnant and breastfeeding women should consult their healthcare provider before using Naproxen D 250.

Drug Interactions:

Naproxen D 250 may interact with other medications, altering their efficacy or increasing the risk of side effects. Patients should avoid concomitant use of Naproxen D 250 with other NSAIDs, anticoagulants, antiplatelet drugs, corticosteroids, selective serotonin reuptake inhibitors (SSRIs), and certain herbal supplements like St. John's wort. Combining Naproxen D 250 with alcohol or tobacco may also increase the risk of gastrointestinal bleeding and other adverse effects. Patients should always consult their healthcare provider before starting or discontinuing any medications.

Conclusion:

Naproxen D 250 is a unique pharmaceutical formulation that combines the analgesic and anti-inflammatory properties of Naproxen with the gastrointestinal benefits of Domperidone SR. This combination offers effective relief from pain and gastrointestinal symptoms associated with various conditions. However, it is essential to use Naproxen D 250 judiciously, following the prescribed dosage and precautions to minimize the risk of adverse effects. Patients should consult their healthcare provider for personalized guidance and monitoring while using Naproxen D 250 for optimal therapeutic outcomes. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

 For further information: 

 EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

 CALL/WHATSAPP: 7877551268, 7849827488

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