Naproxen (500mg), Domperidone SR (30mg) & NAPROXZEN D 500 : Tablet - Steris Healthcare PVT LTD………

Naproxen (500mg), Domperidone SR (30mg) & NAPROXZEN D 500 

Naproxen (500mg) and Domperidone SR (30mg). This medication is designed to provide comprehensive relief from pain and inflammation while addressing associated gastrointestinal discomforts. In this article, we will delve into the uses, benefits, mechanisms, dosage, side effects, and precautions of NAPROXZEN D 500, ensuring a thorough understanding of its applications and safety considerations.

Understanding Naproxen

What is Naproxen?

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to reduce inflammation, pain, and fever. It works by inhibiting the production of prostaglandins, which are chemicals responsible for inflammation and pain in the body. Naproxen is effective in treating a variety of conditions, including arthritis, muscle pain, menstrual cramps, and other acute pain conditions.

Benefits of Naproxen

1. Anti-inflammatory Properties: Naproxen effectively reduces inflammation, providing relief from conditions like rheumatoid arthritis and osteoarthritis.
2. Pain Relief: It alleviates various types of pain, including headaches, muscle pain, and dental pain.
3. Fever Reduction: Naproxen can reduce fever, making it useful for managing symptoms of infections and illnesses.
4. Long-Lasting Effect: It has a relatively long half-life, providing sustained relief from pain and inflammation.

Mechanism of Action

Naproxen works by blocking the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). These enzymes are involved in the synthesis of prostaglandins, which mediate inflammation, pain, and fever. By inhibiting these enzymes, Naproxen reduces the levels of prostaglandins, thereby decreasing inflammation and pain.

Understanding Domperidone SR

What is Domperidone SR?

Domperidone SR (sustained release) is a medication that enhances gastrointestinal motility and alleviates symptoms of nausea and vomiting. It works by blocking dopamine receptors in the gastrointestinal tract, which helps to increase the movement of the stomach and intestines, promoting smoother digestion and reducing discomfort.

Benefits of Domperidone SR

1. Anti-Nausea: Domperidone is highly effective in reducing nausea and vomiting, making it useful for patients experiencing these symptoms due to various causes.
2. Improved Gastric Motility: It enhances the movement of the stomach and intestines, aiding in the digestion process and preventing gastrointestinal stasis.
3. Relief from Gastric Discomfort: Domperidone helps alleviate symptoms like bloating, fullness, and heartburn associated with slow gastric emptying.

Mechanism of Action

Domperidone works by blocking dopamine D2 receptors in the chemoreceptor trigger zone and the gastrointestinal tract. This action prevents nausea and vomiting signals from reaching the brain and stimulates the movement of the stomach and intestines, promoting faster gastric emptying and improved digestion.

The Synergy of NAPROXZEN D 500

NAPROXZEN D 500 combines the anti-inflammatory and pain-relieving properties of Naproxen with the prokinetic and anti-nausea effects of Domperidone SR. This combination addresses not only the pain and inflammation but also the gastrointestinal side effects that often accompany the use of NSAIDs.

Benefits of NAPROXZEN D 500

1. Comprehensive Pain Relief: Naproxen provides robust pain relief, while Domperidone ensures that gastrointestinal discomforts are managed effectively.
2. Enhanced Patient Compliance: The combination reduces the need for multiple medications, simplifying the treatment regimen for patients.
3. Reduced Gastrointestinal Side Effects: Domperidone mitigates the common gastrointestinal side effects associated with NSAIDs, such as nausea, vomiting, and gastric irritation.
4. Improved Quality of Life: Patients experience better overall relief from pain and gastrointestinal discomfort, enhancing their daily functioning and quality of life.

Indications and Uses

NAPROXZEN D 500 is indicated for the management of various conditions, including:

1. Arthritis: Relief from pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
2. Acute Pain: Management of acute pain conditions such as muscle pain, dental pain, and postoperative pain.
3. Menstrual Cramps: Alleviation of pain and discomfort during menstruation.
4. Migraine: Reduction of pain and associated nausea in migraine patients.
5. Gastrointestinal Symptoms: Prevention and treatment of nausea and vomiting, especially in patients using NSAIDs.

Dosage and Administration

Dosage

The typical dosage of NAPROXZEN D 500 is one tablet taken twice daily, preferably after meals. The exact dosage and duration of treatment should be determined by a healthcare professional based on the patient's condition and response to therapy.

Administration

• Oral Intake: NAPROXZEN D 500 should be taken orally with a full glass of water.
• Food Intake: It is recommended to take the medication after meals to minimize gastrointestinal irritation.
• Consistency: Take the medication at the same time each day to maintain consistent blood levels and maximize therapeutic effects.

Side Effects and Precautions

Common Side Effects

1. Gastrointestinal: Stomach pain, nausea, constipation, diarrhea, and indigestion.
2. Central Nervous System: Headache, dizziness, and drowsiness.
3. Skin: Rash, itching, and photosensitivity.

Drug Interactions

NAPROXZEN D 500 may interact with several medications, including:

1. Antihypertensives: Reduced effectiveness of blood pressure medications.
2. Diuretics: Increased risk of kidney problems.
3. Lithium: Elevated lithium levels and potential toxicity.
4. Methotrexate: Increased risk of methotrexate toxicity.

Patients should inform their healthcare provider about all medications they are taking to avoid potential interactions and ensure safe use.

Conclusion

NAPROXZEN D 500 is a potent combination medication that offers comprehensive relief from pain, inflammation, and gastrointestinal discomfort. Combining Naproxen (500mg) and Domperidone SR (30mg) addresses both the primary symptoms and the common side effects associated with NSAID use. Patients using NAPROXZEN D 500 can expect effective management of their conditions with improved quality of life. However, it is essential to use this medication under medical supervision, considering potential side effects and drug interactions. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

 For further information: 

 EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

 CALL/WHATSAPP: 7877551268, 7849827488

 BUY NOW