Nicorandil (10mg) & MAYORANDIL 10 Mg : Online at Upto 30% OFF…..

May 29, 2024

MAYORANDIL 10 Mg

Nicorandil (10mg)

Nicorandil (10mg), marketed under the brand name MAYORANDIL 10 Mg, is a medication primarily used to manage angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart. This pharmaceutical belongs to a class of drugs known as potassium channel activators, which have both vasodilatory and nitrate-like properties. Nicorandil is a well-tolerated and effective option for patients who require long-term management of angina, especially those who may not respond adequately to traditional anti-anginal therapies.

Uses

Management of Angina Pectoris

  • Stable Angina: Nicorandil is effective in managing stable angina, where chest pain occurs predictably with physical exertion or stress.
  • Unstable Angina: It is also used in cases of unstable angina, where chest pain occurs unpredictably, posing a higher risk of heart attack.
  • Combination Therapy: Nicorandil can be used in combination with other medications such as beta-blockers, calcium channel blockers, and nitrates to enhance therapeutic efficacy.

Cardioprotective Effects

  • Post-Myocardial Infarction: It helps in reducing the risk of recurrent angina and cardiac events in patients who have suffered a myocardial infarction.
  • Coronary Artery Disease: Nicorandil aids in improving blood flow and oxygen delivery to the heart muscles, making it beneficial for patients with coronary artery disease.

Dosage

Standard Dosage

  • Initial Dose: The typical starting dose of Nicorandil is 5 mg twice daily.
  • Maintenance Dose: The dose can be increased to 10 mg twice daily based on the patient's response and tolerance.
  • Maximum Dose: In some cases, the dosage may be further adjusted to a maximum of 20 mg twice daily.

Administration Guidelines

  • Timing: Nicorandil should be taken at regular intervals, preferably at the same times each day, to maintain consistent blood levels.
  • With or Without Food: It can be taken with or without food, but it is advisable to follow the healthcare provider's instructions regarding meals.
  • Missed Dose: If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next dose. Do not double the dose to make up for the missed one.

Side Effects

Common Side Effects

  • Headache: A common initial side effect that usually subsides with continued use.
  • Flushing: A warm sensation or redness in the skin, particularly on the face.
  • Dizziness: Patients may experience light-headedness, especially when standing up quickly.

Serious Side Effects

  • Ulceration: Nicorandil can cause gastrointestinal ulceration, including mouth ulcers.
  • Hypotension: Low blood pressure, which can lead to fainting or severe dizziness.
  • Allergic Reactions: Rash, itching, or swelling, particularly of the face, tongue, or throat, and severe dizziness.

Precautions

Before Taking Nicorandil

  • Medical History: Inform the healthcare provider about any history of heart problems, liver disease, or ulcers.
  • Allergies: Report any known allergies to medications or substances.

During Treatment

  • Regular Monitoring: Regular check-ups are necessary to monitor the drug’s effectiveness and any adverse effects.
  • Alcohol Consumption: Limit or avoid alcohol as it can exacerbate side effects like dizziness.
  • Driving and Operating Machinery: Be cautious when driving or operating machinery until you know how Nicorandil affects you, as it can cause dizziness or light-headedness.

Interactions

Drug Interactions

  • Nitrates: Concurrent use with other nitrates or nitric oxide donors can lead to severe hypotension.
  • Antihypertensives: Nicorandil can enhance the blood pressure-lowering effects of antihypertensive drugs.
  • Phosphodiesterase Inhibitors: Drugs like sildenafil (Viagra) can interact with Nicorandil, leading to increased risk of low blood pressure.

Food and Lifestyle Interactions

  • Grapefruit Juice: Avoid grapefruit juice as it can affect the metabolism of Nicorandil.
  • Diet: Maintain a balanced diet and stay hydrated to help manage side effects and overall health.

Conclusion

Nicorandil (10mg), marketed as MAYORANDIL 10 Mg, is a potent medication for managing angina pectoris, offering both vasodilatory and nitrate-like benefits. While effective, it is essential to adhere to prescribed dosages, be aware of potential side effects, and take necessary precautions. Regular consultations with a healthcare provider will ensure optimal use and monitoring, enhancing the therapeutic outcomes and minimizing risks. Always consult your healthcare provider for personalized advice and treatment plans. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

 EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

 CALL/WHATSAPP: 7877551268, 7849827488

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