Nicorandil (5 mg) & MAYORANDIL 5 Mg : Side Effects, Uses, Interactions, and Alternatives

May 29, 2024

MAYORANDIL 5 Mg

Nicorandil (5 mg)

Nicorandil 5 mg, sold under the brand name MAYORANDIL 5 Mg, is a medication primarily used for the treatment of angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart. Angina can significantly impact the quality of life, and managing its symptoms is crucial for maintaining heart health. Nicorandil is a unique drug that combines the properties of a nitrate with those of a potassium channel opener, offering effective relief from angina symptoms.

Uses

Nicorandil (5mg) is prescribed for various cardiovascular conditions, particularly:

1. Angina Pectoris

  • Chronic Stable Angina: Helps to prevent angina attacks during daily activities and stress.
  • Unstable Angina: Used in the management of acute episodes of chest pain.

2. Heart Failure

  • Adjunct Therapy: Can be used as an adjunct to standard heart failure treatments to improve symptoms and exercise capacity.

3. Hypertension

  • Off-Label Use: Sometimes prescribed off-label for its vasodilatory effects to manage high blood pressure.

Dosage

The dosage of Nicorandil (5mg) should be determined by a healthcare professional based on the patient's medical condition, response to treatment, and other medications they may be taking. The typical dosage guidelines include:

Initial Dosage

  • Starting Dose: The usual starting dose is 5mg twice daily.
  • Adjustment: Depending on the patient's response, the dose may be gradually increased.

Maintenance Dosage

  • Standard Dose: The maintenance dose usually ranges from 10mg to 20mg twice daily.
  • Maximum Dose: In some cases, the dose can be increased up to 30mg twice daily, under strict medical supervision.

Administration

  • With or Without Food: Nicorandil can be taken with or without food. However, it should be taken at the same times each day to maintain consistent blood levels.

Side Effects

Like all medications, Nicorandil (5mg) may cause side effects. Not everyone experiences these side effects, and they often diminish as the body adjusts to the medication. Common side effects include:

Common Side Effects

  • Headache: A frequent side effect, often diminishing over time.
  • Dizziness: May occur due to blood pressure changes.
  • Flushing: A warm sensation, particularly on the face.

Serious Side Effects

  • Mouth Ulcers: Persistent ulcers that require medical attention.
  • Hypotension: Severe drops in blood pressure, leading to dizziness or fainting.
  • Allergic Reactions: Rash, itching, swelling, severe dizziness, and difficulty breathing.

Precautions

Before taking Nicorandil (5mg), certain precautions should be considered to ensure safety and efficacy:

Medical History

  • Heart Conditions: Inform your doctor if you have any heart conditions other than angina.
  • Blood Pressure Issues: Discuss any history of low blood pressure or heart failure.
  • Kidney or Liver Disease: These conditions may require dose adjustments.

Drug Interactions

  • Nitrates: Avoid using other nitrate medications simultaneously.
  • Phosphodiesterase Inhibitors: Medications like sildenafil can interact with Nicorandil.
  • Blood Pressure Medications: May enhance hypotensive effects.

Lifestyle Considerations

  • Alcohol: Limit alcohol intake as it can exacerbate dizziness.
  • Driving and Machinery: Avoid activities requiring alertness until you know how the medication affects you.

Pregnancy and Breastfeeding

  • Pregnancy: Nicorandil should be used during pregnancy only if clearly needed.
  • Breastfeeding: It is not known if Nicorandil passes into breast milk. Consult your doctor.

Conclusion

Nicorandil (5mg), marketed as MAYORANDIL, is an effective treatment for angina pectoris, offering a unique mechanism of action that combines vasodilation with potassium channel activation. Proper adherence to prescribed dosages and awareness of potential side effects and interactions can maximize its benefits while minimizing risks. Always consult your healthcare provider for personalized advice and adjustments based on your specific health needs. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

 EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

 CALL/WHATSAPP: 7877551268, 7849827488

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