Olmesartan (40mg),(5mg) Amlodipine ,(12.5mg) HCTZ

Jun 23, 2023

Olmesartan (40mg), Amlodipine (5mg), HCTZ (12.5mg)

Olmesartan medoxomil amlodipine and hydrochlorothiazide tablets are a potent combination therapy for patients struggling with high blood pressure (hypertension). Marketed under the brand name TRIOLMISTRUM 40, these tablets combine Olmesartan (40 mg), Amlodipine (5 mg), and Hydrochlorothiazide (12.5 mg) in a single, easy-to-take formulation. The combination is designed to provide effective blood pressure control, reduce cardiovascular risks, and improve overall heart health.

The main advantage of olmesartan medoxomil amlodipine and hydrochlorothiazide tablets is their ability to target multiple mechanisms that contribute to high blood pressure. Olmesartan 40 mg works by blocking angiotensin II receptors, Amlodipine 5 mg relaxes blood vessels, and Hydrochlorothiazide 12.5 mg helps eliminate excess salt and water, making TRIOLMISTRUM 40 a comprehensive and convenient option for patients.

What is Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide?

Olmesartan medoxomil amlodipine and hydrochlorothiazide tablets are a combination of three antihypertensive agents:

  • Olmesartan (40 mg): An angiotensin II receptor blocker (ARB) that helps relax blood vessels and improve blood flow.

  • Amlodipine (5 mg): A calcium channel blocker that reduces vascular resistance and helps lower blood pressure.

  • Hydrochlorothiazide (12.5 mg): A thiazide diuretic that removes excess water and sodium from the body, reducing fluid overload and blood pressure.

Together, these three components act synergistically to maintain healthy blood pressure levels and reduce the risk of heart attack, stroke, and kidney complications.

Uses of TRIOLMISTRUM 40

Olmesartan medoxomil amlodipine and hydrochlorothiazide tablets are primarily used for:

  1. Hypertension (High Blood Pressure):

    • Effective in controlling moderate to severe high blood pressure

    • Reduces the risk of cardiovascular events like stroke and heart attack

  2. Cardiovascular Risk Reduction:

    • Helps prevent damage to the heart, kidneys, and blood vessels caused by prolonged hypertension

  3. Combination Therapy Benefits:

    • Suitable for patients not adequately controlled with single or dual antihypertensive therapy

    • Simplifies treatment by reducing pill burden and improving compliance

The combination therapy makes TRIOLMISTRUM 40 ideal for patients who need a strong, multi-targeted approach to hypertension management.

How Does TRIOLMISTRUM 40 Work?

The mechanism of action of olmesartan medoxomil amlodipine and hydrochlorothiazide tablets is multi-pronged:

  • Olmesartan 40 mg: Blocks the angiotensin II receptor, preventing blood vessel constriction and reducing aldosterone release.

  • Amlodipine 5 mg: Inhibits calcium entry into vascular smooth muscle, causing vasodilation and lowering peripheral resistance.

  • Hydrochlorothiazide 12.5 mg: Promotes sodium and water excretion via the kidneys, decreasing blood volume and pressure.

This combined action ensures comprehensive control of blood pressure while minimizing the risk of complications related to uncontrolled hypertension.

Dosage and Administration

TRIOLMISTRUM 40 should be taken exactly as prescribed by your healthcare provider. General guidance:

  • Usually taken once daily, with or without food

  • Swallow the tablet whole with water; do not crush or chew

  • Regular monitoring of blood pressure is recommended to adjust the dose if needed

Patients should not stop the medication abruptly as it may cause a sudden increase in blood pressure. Follow your doctor’s instructions carefully to achieve optimal results.

Side Effects of TRIOLMISTRUM 40

Olmesartan medoxomil amlodipine and hydrochlorothiazide tablets are generally well-tolerated, but some patients may experience:

  • Dizziness or lightheadedness

  • Swelling of hands, feet, or ankles (common with amlodipine)

  • Headache

  • Increased urination or mild dehydration (due to hydrochlorothiazide)

  • Rarely, severe allergic reactions or kidney problems

It is important to inform your doctor immediately if you experience severe side effects, particularly swelling, fainting, or persistent dizziness.

Why Choose Steris Healthcare?

Choosing Steris Healthcare ensures patients receive high-quality, safe, and reliable medications. Our TRIOLMISTRUM 40 tablets offer:

  • WHO-GMP certified manufacturing with strict quality control

  • Affordable pricing and wide availability across India

  • Expert guidance for safe and effective use

Steris Healthcare is dedicated to improving patient health and compliance, making it a trusted choice for hypertension management.

Frequently Asked Questions

Q1: Can TRIOLMISTRUM 40 be taken by elderly patients?
A: Yes, but dosing may be adjusted based on kidney function and other health conditions. Regular monitoring is recommended.

Q2: Can I take olmesartan medoxomil amlodipine and hydrochlorothiazide tablets with other medications?
A: Always consult your doctor before combining medications. Some drugs, including NSAIDs and other antihypertensives, may interact.

Q3: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember. If it is close to the next dose, skip the missed one. Do not double the dose.

Q4: Can I take TRIOLMISTRUM 40 during pregnancy?
A: No, ARBs like olmesartan should be avoided during pregnancy. Consult your doctor for alternative options.

Q5: How long does it take to see the effect of TRIOLMISTRUM 40?
A: Most patients notice blood pressure improvement within 1–2 weeks, but optimal effects may take several weeks.

Conclusion

Olmesartan medoxomil amlodipine and hydrochlorothiazide tablets provide a comprehensive and convenient solution for managing high blood pressure. By targeting multiple pathways that contribute to hypertension, TRIOLMISTRUM 40 helps reduce cardiovascular risk and maintain long-term heart and kidney health.

If you or a loved one are struggling with uncontrolled blood pressure, consult your doctor about TRIOLMISTRUM 40 today.

Take charge of your heart health with Steris Healthcare – trusted, reliable, and patient-friendly medications.

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