Pantoprazole (40mg), Itopride (150mg) & PANTOSTRUM IT : Tablet Comprehensive guide to MedlinePlus Drug Information….

May 16, 2024

PANTOSTRUM IT 

Pantoprazole (40mg), Itopride (150mg)

PANTOSTRUM IT is a  Pantoprazole (40mg), Itopride (150mg) combination medication designed to treat various gastrointestinal disorders. It combines Pantoprazole, a proton pump inhibitor (PPI), with Itopride, a prokinetic agent. This article delves into the uses, benefits, mechanisms, and important considerations of PANTOSTRUM IT, providing a thorough understanding of this powerful medication.

Understanding Pantoprazole and Itopride

  • Pantoprazole (40mg): Pantoprazole is a proton pump inhibitor that reduces stomach acid production, making it effective in treating conditions like GERD, peptic ulcers, and Zollinger-Ellison syndrome.
  • Itopride (150mg): Itopride is a prokinetic agent that enhances gastrointestinal motility, making it beneficial in treating functional dyspepsia and other related conditions.

Mechanism of Action

  • Pantoprazole: Works by irreversibly binding to and inhibiting the hydrogen-potassium ATPase enzyme system (the proton pump) on the gastric parietal cells, leading to a significant reduction in stomach acid production.
  • Itopride: Enhances gastrointestinal motility by antagonizing dopamine D2 receptors and inhibiting the enzyme acetylcholinesterase, which increases acetylcholine levels and promotes gastric emptying and movement of the intestines.

Indications for Use

  • Gastroesophageal Reflux Disease (GERD): Effective in reducing symptoms such as heartburn, acid regurgitation, and esophagitis.
  • Functional Dyspepsia: Helps alleviate symptoms such as bloating, nausea, and early satiety.
  • Peptic Ulcers: Promotes healing of stomach and duodenal ulcers by reducing acid secretion and improving gastric motility.
  • Zollinger-Ellison Syndrome: Manages symptoms of this rare condition characterized by excessive acid production.

Benefits of PANTOSTRUM IT

  • Dual Action: Combines acid reduction with improved gastrointestinal motility, providing comprehensive relief from gastrointestinal symptoms.
  • Effective Symptom Management: Reduces heartburn, bloating, nausea, and other discomforts associated with gastrointestinal disorders.
  • Enhanced Healing: Promotes the healing of ulcers and erosions in the stomach and duodenum.
  • Improved Quality of Life: Helps patients manage chronic gastrointestinal conditions effectively, improving their overall well-being.

Dosage and Administration

  • Pantoprazole (40mg): Typically taken once daily, preferably before a meal, to reduce stomach acid production.
  • Itopride (150mg): Generally administered three times daily before meals to enhance gastrointestinal motility.
  • Combination Therapy: The specific dosage and duration of treatment should be determined by a healthcare provider based on the patient's condition and response to therapy.

Potential Side Effects

  • Pantoprazole: Headache, diarrhea, nausea, abdominal pain, flatulence, dizziness, and joint pain. Long-term use may lead to vitamin B12 deficiency and increased risk of bone fractures.
  • Itopride: Diarrhea, abdominal pain, increased salivation, dizziness, fatigue, and allergic reactions. Rarely, it may cause extrapyramidal symptoms such as tremors or muscle stiffness.

Precautions and Warnings

  • Allergies: Patients allergic to Pantoprazole, Itopride, or any other component of PANTOSTRUM IT should avoid this medication.
  • Drug Interactions: Inform your healthcare provider about all medications you are taking, as there can be significant interactions, especially with anticoagulants, antiplatelet agents, and certain antibiotics.
  • Pregnancy and Breastfeeding: Consult a healthcare provider before using PANTOSTRUM IT if you are pregnant or breastfeeding.
  • Long-term Use: Prolonged use of Pantoprazole may require monitoring for vitamin B12 levels and bone health.

Contraindications

  • Hypersensitivity: Known hypersensitivity to Pantoprazole, Itopride, or any other ingredients in PANTOSTRUM IT.
  • Gastrointestinal Bleeding: Should not be used in patients with active gastrointestinal bleeding or perforation.
  • Severe Liver Disease: Patients with severe liver impairment should use this medication with caution.

Patient Advice

  • Adherence to Treatment: It is essential to take PANTOSTRUM IT exactly as prescribed by your healthcare provider to achieve the best results.
  • Lifestyle Modifications: Complement the medication with lifestyle changes such as avoiding spicy foods, reducing caffeine and alcohol intake, and eating smaller, more frequent meals.
  • Regular Follow-ups: Keep regular appointments with your healthcare provider to monitor your condition and adjust the treatment as necessary.
  • Report Side Effects: Immediately report any severe or unusual side effects to your healthcare provider.

Conclusion

PANTOSTRUM IT, combining Pantoprazole and Itopride, offers a powerful solution for managing a variety of gastrointestinal disorders. Its dual-action mechanism effectively reduces stomach acid and enhances gastrointestinal motility, providing comprehensive relief from symptoms and promoting healing. Always use this medication under the guidance of a healthcare provider to ensure safety and efficacy. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

 

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

CALL/WHATSAPP: 7877551268, 7849827488

 

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