"ESMOStrum HP Kit: Clarithromycin, Esomeprazole & Amoxicillin"

Introduction

ESMOSTRUM HP KIT is a clinically proven combination therapy for the treatment of H. pylori infections, commonly associated with peptic ulcer disease, gastritis, and gastric malignancies. This triple-drug therapy includes:

• Esomeprazole – a proton pump inhibitor (PPI) that reduces stomach acid

• Amoxicillin – a broad-spectrum penicillin antibiotic

• Clarithromycin – a macrolide antibiotics with high anti-H. pylori activity

The coordinated action of these three agents ensures effective bacterial eradication, mucosal healing, and symptom relief.

Kit Composition

Each ESMOSTRUM HP KIT contains:

• 1 tablet of Esomeprazole Gastro-Resistant 40 mg

• 1 tablet of Amoxicillin 750 mg

• 1 tablet of Clarithromycin 500 mg

Uses / Indications

ESMOSTRUM HP KIT is primarily used for:

• Eradication of Helicobacter pylori (H. pylori)

• Treatment and prevention of duodenal and gastric ulcers

• Management of chronic active gastritis

• Reducing the risk of ulcer recurrence

It is a first-line therapy recommended by international gastroenterology guidelines for H. pylori management.

Mechanism of Action

• Esomeprazole (40 mg):
  Reduces gastric acid secretion by inhibiting the H⁺/K⁺ ATPase enzyme in parietal cells. Creates a low-acid environment that enhances antibiotic effectiveness.

• Amoxicillin (750 mg):
  Bactericidal action by inhibiting bacterial cell wall synthesis. Active against gram-positive and gram-negative bacteria, including H. pylori.

• Clarithromycin (500 mg):
  Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Highly effective against H. pylori strains.

Key Benefits of ESMOSTRUM HP KIT

• Triple-action therapy for complete eradication of H. pylori infection

• Helps in ulcer healing and prevents recurrence

• Reduces gastric mucosal inflammation and related symptoms like pain, bloating, and acid reflux

• Convenient once-daily kit packaging for better patient compliance

• Backed by international guidelines for H. pylori management

• Enteric-coated PPI ensures acid suppression even in acidic stomach conditions

• Antibiotics are dosed effectively to prevent bacterial resistance

Dosage and Administration

Typical Dosage:

• One kit (3 tablets) twice a day – 1 hour before meals, usually for 7 to 14 days

Instructions:

• Swallow tablets whole with water

• Complete full course, even if symptoms resolve early

• Avoid skipping doses to prevent resistance and relapse

Side Effects and Precautions

Common Side Effects:

• Nausea

• Diarrhea

• Headache

• Metallic taste (from Clarithromycin)

• Abdominal discomfort

Precautions:

• Avoid in patients allergic to penicillins or macrolides

• Use with caution in patients with hepatic or renal impairment

• Can cause Clostridium difficile-associated diarrhea – monitor for prolonged diarrhea

• May interact with drugs like statins, warfarin, theophylline, and antacids

FAQs (Frequently Asked Questions)

Q1. What is the purpose of ESMOSTRUM HP KIT?
It is used to eradicate H. pylori infection and heal ulcers caused by this bacterium in the stomach or duodenum.

Q2. How long should I take this kit?
Usually for 7 to 14 days, as prescribed by your doctor. Do not stop early even if symptoms improve.

Q3. Can I take this kit with food?
It is best taken 1 hour before meals, twice daily, to ensure optimal absorption.

Q4. What should I avoid during the therapy?
Avoid alcohol, spicy food, smoking, and NSAIDs during the treatment course.

Q5. Is it safe for children or pregnant women?
This kit is typically not recommended for children unless prescribed. Pregnant or lactating women should use it only under strict medical supervision.

Conclusion

ESMOSTRUM HP KIT offers a complete, guideline-recommended solution for H. pylori eradication. With the triple strength of Esomeprazole, Amoxicillin, and Clarithromycin, it ensures rapid symptom relief, healing of ulcers, and prevention of recurrence.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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