Rabeprazole (20mg), Itopride (150mg SR)````````

Dec 01, 2023

Gastrointestinal disorders such as acid reflux, heartburn, dyspepsia, and delayed gastric emptying affect millions of people in India, often reducing quality of life and interfering with daily activities. For patients experiencing persistent stomach acidity, bloating, or upper abdominal discomfort, effective and reliable therapy is essential. RABISTRUM IT is a clinically advanced combination medication that brings together Rabeprazole 20 mg, a potent proton pump inhibitor (PPI), and Itopride 150 mg SR, a prokinetic agent, offering comprehensive relief from acid-related and motility disorders.

This combination works synergistically: Rabeprazole reduces gastric acid secretion to protect the stomach lining, while Itopride enhances gastrointestinal motility, promoting faster digestion and reducing symptoms like bloating, fullness, and nausea. Together, these agents provide fast-acting and long-lasting relief, making RABISTRUM IT a preferred choice for patients suffering from chronic gastrointestinal discomfort, GERD, and functional dyspepsia.

Uses of RABISTRUM IT

Rabeprazole 20mg and Itopride 150mg SR is indicated for a range of acid-related and motility disorders, including:

1. Gastroesophageal Reflux Disease (GERD)

  • Reduces heartburn, regurgitation, and esophageal irritation caused by acid reflux

  • Protects esophageal mucosa from long-term acid exposure

2. Functional Dyspepsia

  • Addresses upper abdominal discomfort, bloating, and early satiety

  • Helps in improving gastric emptying

3. Gastritis and Peptic Ulcer Disease

  • Rabeprazole helps heal stomach and duodenal ulcers

  • Reduces pain, irritation, and ulcer recurrence

4. Nausea and Bloating

  • Itopride accelerates gastric emptying

  • Relieves post-meal fullness, nausea, and bloating

5. Combination Therapy for Complex GI Disorders

  • Useful in patients with both acid hypersecretion and delayed gastric motility

  • Enhances overall symptom control

Benefits of RABISTRUM IT

1. Comprehensive Dual-Action Relief

  • Rabeprazole 20 mg: Suppresses excessive stomach acid

  • Itopride 150 mg SR: Improves gastric motility and digestion

  • Addresses both cause and symptoms of gastrointestinal discomfort

2. Effective Symptom Control

  • Reduces heartburn, regurgitation, bloating, and nausea

  • Alleviates abdominal discomfort associated with GERD and functional dyspepsia

3. Supports Ulcer Healing

  • Rabeprazole promotes faster healing of gastric and duodenal ulcers

  • Reduces the risk of complications like bleeding or perforation

4. Long-Lasting Effects

  • Sustained-release Itopride ensures continuous motility support

  • Combined effect ensures prolonged symptom relief

5. Improves Quality of Life

  • Reduces discomfort, improves digestion, and enhances appetite

  • Helps patients regain normal daily activity levels

6. Convenient Combination Therapy

  • Single tablet containing both PPI and prokinetic

  • Reduces pill burden for patients

Dosage and Method of Administration

Recommended Dosage

  • Adults: 1 tablet of RABISTRUM IT once daily, preferably before breakfast

  • Follow the dosage prescribed by a healthcare professional

Method of Intake

  • Swallow the tablet whole with water

  • Do not crush, chew, or break the sustained-release tablet

Duration of Treatment

  • Acute conditions: Typically 4–8 weeks

  • Chronic or maintenance therapy: As advised by your doctor

  • Regular follow-up is recommended to assess treatment effectiveness

Side Effects of RABISTRUM IT

While RABISTRUM IT is generally well-tolerated, some patients may experience mild side effects.

Common Side Effects

  • Headache

  • Dizziness

  • Mild diarrhea or constipation

  • Abdominal discomfort

Less Common Side Effects

  • Fatigue

  • Nausea

  • Dry mouth

  • Flatulence

Rare Side Effects

  • Allergic reactions such as rash, itching, or swelling

  • Severe gastrointestinal symptoms (persistent vomiting or abdominal pain)

  • Liver function abnormalities

Patients experiencing severe or persistent side effects should seek immediate medical attention.

Precautions and Warnings

General Precautions

  • For oral use only

  • Take on an empty stomach for optimal absorption

  • Avoid self-medicating for chronic gastrointestinal symptoms

Pre-existing Conditions

  • Use caution in patients with liver disease, kidney disease, or electrolyte imbalance

  • Regular monitoring may be necessary

Allergy Information

  • Do not use if allergic to Rabeprazole, Itopride, or related compounds

Lifestyle Considerations

  • Avoid spicy, oily, or acidic foods which may exacerbate symptoms

  • Maintain a healthy diet and avoid lying down immediately after meals

Storage Instructions

  • Store at room temperature away from moisture and sunlight

  • Keep out of reach of children

Conclusion

RABISTRUM IT is a dual-action gastrointestinal therapy combining Rabeprazole 20 mg and Itopride 150 mg SR to address both acid-related and motility disorders. This combination ensures fast, effective, and long-lasting relief from GERD, functional dyspepsia, gastritis, bloating, and nausea.

By simultaneously reducing gastric acid secretion and promoting gastric emptying, RABISTRUM IT not only treats symptoms but also helps in healing ulcers and improving digestive function. Its once-daily regimen enhances patient compliance, providing convenient and reliable therapy.

Frequently Asked Questions (F&Q)

Can RABISTRUM IT be used for long-term GERD?

  • Yes, but long-term use should be under medical supervision to monitor potential effects on nutrient absorption and gastric microbiota.

Is it safe during pregnancy or breastfeeding?

  • Consult your doctor before use; safety data in pregnancy and lactation is limited. Only use if clearly indicated.

Can it be taken with other medications?

  • Inform your doctor about other acid-reducing medications, antibiotics, or antacids before starting RABISTRUM IT. Drug interactions are possible.

How soon can I expect relief?

  • Symptom improvement may be noticed within few days, but complete relief, especially for ulcer healing, may take 4–8 weeks.

Can I stop the medication abruptly?

  • Do not stop abruptly without consulting your doctor, especially if used for ulcer treatment or chronic GERD.

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