SACUBRIGHT 100 Mg : STERIS Healthcare PVT LTD…...

SACUBRIGHT 100 Mg 

Sacubitril (49mg), Valsartan (51mg)

SACUBRIGHT 100 is a combination medication containing Sacubitril (49mg) and Valsartan (51mg). It is commonly prescribed for the treatment of heart failure with reduced ejection fraction (HFrEF). This comprehensive guide explores the uses, dosage, price, side effects, composition, and other essential information about SACUBRIGHT 100.

Uses of SACUBRIGHT 100

1. Heart Failure: SACUBRIGHT 100 is indicated for the management of symptomatic heart failure with reduced ejection fraction (HFrEF) in adult patients. It helps improve symptoms, reduce hospitalizations due to heart failure, and enhance overall cardiovascular outcomes.
2. Neprilysin Inhibition: Sacubitril, a neprilysin inhibitor, works by increasing the levels of beneficial peptides that promote vasodilation and diuresis, thereby reducing the workload on the heart.
3. Angiotensin Receptor Blockade: Valsartan, an angiotensin receptor blocker (ARB), helps block the effects of angiotensin II, leading to vasodilation, reduced aldosterone secretion, and improved cardiac remodeling.

Dosage of SACUBRIGHT 100

The dosage of SACUBRIGHT 100 is individualized based on the patient's medical history, renal function, and tolerance to the medication. A typical dosage regimen may include:

• Initial dose: 49mg Sacubitril / 51mg Valsartan (one tablet) twice daily.
• Titration: The dosage may be titrated based on the patient's response, with the maximum recommended dose being 97mg Sacubitril / 103mg Valsartan twice daily.

It is crucial to follow the dosage instructions provided by the healthcare provider to achieve optimal therapeutic benefits while minimizing the risk of side effects.

Price of SACUBRIGHT 100

The price of SACUBRIGHT 100 can vary depending on factors such as the brand, dosage strength, and the quantity of tablets in a pack. Generally, it is considered a cost-effective option for the management of heart failure compared to individual components or alternative medications.

Side Effects of SACUBRIGHT 100

While SACUBRIGHT 100 is generally well-tolerated, some individuals may experience mild to moderate side effects. These side effects may include:

1. Hypotension: Due to the vasodilatory effects of Sacubitril and Valsartan, some patients may experience low blood pressure, especially at the initiation of treatment or during dose adjustments.
2. Hyperkalemia: Valsartan, being an ARB, may lead to an increase in serum potassium levels. Regular monitoring of electrolytes is recommended.
3. Renal Impairment: Patients with pre-existing renal impairment or on diuretic therapy may experience worsening renal function. Monitoring of renal function is essential during treatment.
4. Cough: A dry, persistent cough may occur in some patients, although it is less common compared to ACE inhibitors.

It is important to report any persistent or concerning side effects to the healthcare provider for evaluation and management.

Composition of SACUBRIGHT 100

Each SACUBRIGHT 100 tablet contains Sacubitril (49mg) and Valsartan (51mg) as active ingredients. The combination of these medications provides dual inhibition of the neurohormonal pathways involved in heart failure, leading to improved clinical outcomes.

Precautions and Warnings

• SACUBRIGHT 100 should not be used in patients with a history of angioedema related to ACE inhibitors or ARBs.
• Patients with severe hepatic impairment or bilateral renal artery stenosis should use SACUBRIGHT 100 with caution.
• Avoid concomitant use of SACUBRIGHT 100 with ACE inhibitors, aliskiren, or potassium-sparing diuretics without medical supervision.
• Regular monitoring of blood pressure, renal function, and electrolytes is recommended during treatment with SACUBRIGHT 100.

Conclusion

SACUBRIGHT 100, combining Sacubitril and Valsartan, offers a valuable treatment option for patients with heart failure with reduced ejection fraction (HFrEF). By targeting multiple pathways involved in heart failure pathophysiology, it helps improve symptoms and reduce the risk of heart failure-related hospitalizations. Patients should be aware of potential side effects, adhere to prescribed dosages, and undergo regular medical monitoring to optimize treatment outcomes and cardiovascular health. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. Gynecology, Pediatrics, Dental care, and Dermatology. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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