Sevelamer (400mg) & SAVELINER 400 : Tablet - Steris Healthcare PVT LTD………

Sevelamer (400mg) & SAVELINER 400

Sevelamer (400mg) is a phosphate binder commonly used SAVELINER 400 in patients with chronic kidney disease (CKD) to manage hyperphosphatemia. This article explores its uses, side effects, dosage, and mechanisms of action, providing comprehensive information for patients and healthcare providers.

Uses

Sevelamer (400mg) is primarily prescribed for:

• Hyperphosphatemia Management: It helps reduce high phosphate levels in patients with CKD on dialysis by binding dietary phosphate in the digestive tract and preventing its absorption.
• Chronic Kidney Disease (CKD): It is specifically used in patients with CKD to prevent complications associated with elevated phosphate levels, such as vascular calcification and bone disease.

Side Effects

Common side effects of Sevelamer (400mg) may include:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, constipation, and abdominal pain are common side effects.
• Indigestion: Some patients may experience indigestion or discomfort after meals.
• Gas: Increased gas or bloating can occur.
• Fatigue: A feeling of tiredness or fatigue may be reported by some patients.

Severe side effects are rare but can include severe allergic reactions, intestinal blockage, and changes in blood chemistry. Immediate medical attention is required if these occur.

Dosage

The dosage of Sevelamer (400mg) varies based on the condition being treated and patient-specific factors. General guidelines include:

• Hyperphosphatemia: The typical starting dose is 800 to 1600 mg taken with each meal. The dosage can be adjusted by the healthcare provider based on serum phosphate levels and patient response.
• Maintenance Dose: The dose is often adjusted over time to maintain target phosphate levels, with regular monitoring by the healthcare provider.

Patients should follow the prescribed dosage and not exceed the recommended amount without consulting a healthcare provider.

Mechanism of Action

Sevelamer works by:

• Phosphate Binding: In the digestive tract, Sevelamer binds to dietary phosphate, forming an insoluble complex that is excreted in the feces. This reduces the amount of phosphate absorbed into the bloodstream.
• Non-Calcium-Based Binder: Unlike calcium-based phosphate binders, Sevelamer does not increase calcium levels in the blood, making it a safer option for patients at risk of hypercalcemia.

Conclusion

Sevelamer (400mg) is an effective medication for managing hyperphosphatemia in patients with CKD on dialysis. Understanding its uses, potential side effects, proper dosage, and mechanisms of action can help ensure safe and effective treatment. For personalized advice and optimal results, consulting with healthcare professionals is recommended. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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