Tacrolimus (0.50 mg) - Extended-Release Formula…..

Introduction

TACRENOLIME 0.50 contains Tacrolimus (0.50 mg), a powerful immunosuppressant medication primarily used to prevent organ rejection in transplant patients. It works by suppressing the immune system to stop it from attacking the newly transplanted organ. Tacrolimus is also used in some cases to treat autoimmune diseases or severe eczema under a doctor’s supervision.

Key Benefits of TACRENOLIME 0.50

• Prevents organ rejection after liver, kidney, or heart transplants

• Helps manage autoimmune conditions such as lupus nephritis or myasthenia gravis

• Reduces inflammation in chronic eczema (topical formulations)

• Maintains transplant success by balancing immune response

• Available in precise low-dose (0.50 mg) to tailor therapy

Tacrolimus (0.50 mg) Capsule Uses

• Post-transplant immunosuppression (kidney, liver, heart)

• Autoimmune diseases (in select cases)

• Part of multi-drug immunosuppressive regimens

• Treatment of severe eczema or atopic dermatitis (topical form only)

Dosage & Administration

• Typical starting dose is based on body weight and medical condition

• Taken orally on an empty stomach for better absorption

• Do not crush or chew the capsule

• Regular blood tests are required to monitor Tacrolimus levels

• Dose adjustments may be needed based on response and kidney/liver function

Note: Never self-adjust the dose; always follow the doctor’s instructions carefully.

Side Effects of Tacrolimus (0.50 mg)

Common Side Effects:

• Headache

• Tremors or shakiness

• High blood sugar

• Increased blood pressure

• Nausea or diarrhea

Serious Side Effects:

• Kidney damage (nephrotoxicity)

• Neurotoxicity (confusion, seizures)

• Increased risk of infections

• Electrolyte imbalance (low magnesium or potassium)

• Liver problems

Immediate medical attention is required for symptoms like chest pain, vision changes, or severe dizziness.

Precautions & Warnings

• Regular kidney and liver function tests are essential

• Avoid grapefruit juice (can affect Tacrolimus levels)

• Not advised in pregnancy unless clearly necessary

• May increase risk of cancer or infections with long-term use

• Avoid live vaccines during treatment

FAQs – TACRENOLIME 0.50 (Tacrolimus 0.50 mg)

Q1: How long will I need to take Tacrolimus after transplant?
You may need to take it lifelong to prevent rejection, under regular monitoring.

Q2: Can I stop taking it if I feel fine?
No. Stopping Tacrolimus can lead to organ rejection. Always consult your doctor.

Q3: Can it be taken with food?
It’s best taken without food, preferably 1 hour before or 2 hours after a meal.

Q4: Is this the same Tacrolimus used in eczema creams?
The oral capsule is used for organ rejection, while the topical cream form is for eczema.

Q5: What monitoring is needed during treatment?
You’ll need blood level checks, kidney/liver tests, and blood pressure monitoring.

Conclusion

TACRENOLIME 0.50, containing Tacrolimus (0.50 mg), is a critical immunosuppressant that plays a life-saving role in transplant care and selected autoimmune conditions. While highly effective, it requires careful dosing, regular monitoring, and professional supervision due to its potential side effects and interactions. Always follow your healthcare provider’s instructions for safe and effective use.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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