TRI GLIBEN FORTE : Uses, Side Effects, Interactions, Pictures, ...

TRI GLIBEN FORTE 

Glibenclamide (5mg), Metformin HCI (500mg), Pioglitazone (15mg)

TRI GLIBEN FORTE is a combination medication designed for the effective management of type 2 diabetes mellitus. This medication combines three active ingredients: Glibenclamide (5mg), Metformin HCI (500mg), and Pioglitazone (15mg). Together, they provide a comprehensive approach to controlling blood glucose levels in adults who need additional glycemic control beyond diet and exercise.

Composition

• Glibenclamide (5mg): A sulfonylurea that stimulates the pancreas to release more insulin.
• Metformin HCI (500mg): A biguanide that reduces hepatic glucose production and improves insulin sensitivity.
• Pioglitazone (15mg): A thiazolidinedione that increases insulin sensitivity in muscle and adipose tissue.

Therapeutic Uses

• Primary Use: To improve glycemic control in adults with type 2 diabetes mellitus.
• Combination Therapy: Typically prescribed when single or dual therapy does not provide sufficient blood sugar control.

Dosage and Administration

• Standard Dose: One tablet taken once or twice daily with meals, or as directed by a healthcare provider.
• Administration Guidelines: Swallow the tablet whole with a glass of water. Do not crush or chew the tablets.
• Dose Adjustments: May be required based on individual patient response and tolerability.

Mechanism of Action

• Glibenclamide: Works by stimulating the beta cells in the pancreas to release more insulin.
• Metformin HCI: Lowers blood glucose by decreasing hepatic glucose production and increasing insulin sensitivity in peripheral tissues.
• Pioglitazone: Enhances the sensitivity of insulin receptors in muscle and adipose tissue, improving glucose uptake and utilization.

Key Benefits

• Effective Glycemic Control: The combination of Glibenclamide, Metformin, and Pioglitazone provides comprehensive blood glucose regulation.
• Multifaceted Approach: Addresses different aspects of diabetes management, including insulin release, glucose production, and insulin sensitivity.
• Convenient Dosage: A single-tablet formulation simplifies the medication regimen, improving patient compliance.

Potential Side Effects

• Common: Hypoglycemia, gastrointestinal disturbances (nausea, vomiting, diarrhea), weight gain, and edema.
• Serious: Lactic acidosis (rare but serious with Metformin), liver dysfunction, heart failure (Pioglitazone), and allergic reactions. Immediate medical attention is required for these conditions.

Precautions

• Renal Monitoring: Regular assessment of kidney function is essential, particularly due to Metformin.
• Hepatic Considerations: Use with caution in patients with liver diseases.
• Cardiovascular Risk: Pioglitazone is associated with an increased risk of heart failure; patients with heart conditions should be monitored closely.

Drug Interactions

• Other Antidiabetic Medications: May increase the risk of hypoglycemia.
• Alcohol: Can potentiate the effects of Metformin on lactate metabolism, increasing the risk of lactic acidosis.
• Beta-Blockers: May mask the symptoms of hypoglycemia.

Lifestyle and Dietary Advice

• Balanced Diet: Following a diabetes-friendly diet is crucial for managing blood sugar levels.
• Regular Exercise: Physical activity enhances the effectiveness of the medication and overall health.
• Monitoring: Frequent blood sugar monitoring helps in managing and adjusting the treatment plan.

Conclusion

TRI GLIBEN FORTE is an effective combination therapy for managing type 2 diabetes, combining Glibenclamide, Metformin HCI, and Pioglitazone. Its multifaceted approach to controlling blood glucose levels makes it a valuable choice for patients requiring comprehensive diabetes management. Regular consultation with healthcare providers, adherence to prescribed dosages, and lifestyle adjustments are key to achieving the best outcomes with TRI GLIBEN FORTE.Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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