UDCHOLIC SR 450 (Ursodeoxycholic Acid (450 mg) ): explore.......

UDCHOLIC SR 450 

Ursodeoxycholic Acid (450 mg)

UDCHOLIC SR 450, containing Ursodeoxycholic Acid (450 mg), is a sustained-release formulation designed to improve patient compliance and therapeutic efficacy. This article will provide a comprehensive overview of UDCHOLIC SR 450, including its uses, dosage, side effects, and price, ensuring a thorough understanding of this medication.

Uses

UDCHOLIC SR 450 is primarily used for:

1. Primary Biliary Cirrhosis (PBC): UDCA helps in managing primary biliary cirrhosis, a chronic disease that causes progressive destruction of the bile ducts within the liver.
2. Gallstone Dissolution: It is effective in dissolving cholesterol gallstones in patients who prefer a non-surgical approach.
3. Liver Function Improvement: UDCA is used to improve liver function in patients with chronic liver diseases, such as non-alcoholic fatty liver disease (NAFLD) and primary sclerosing cholangitis (PSC).
4. Cholestasis: It helps in reducing cholestasis, a condition where bile flow from the liver is reduced or blocked, which can occur during pregnancy or in patients with certain liver diseases.

Mechanism of Action

UDCA works by several mechanisms to exert its therapeutic effects:

• Bile Acid Composition: It alters the bile acid composition, reducing the concentration of toxic bile acids that can damage liver cells.
• Cholesterol Solubility: UDCA increases the solubility of cholesterol in bile, aiding in the dissolution of cholesterol gallstones.
• Immunomodulatory Effects: It has immunomodulatory properties that help in reducing inflammation and fibrosis in liver tissues.

Dosage

The dosage of UDCHOLIC SR 450 should be determined by a healthcare professional based on the patient's condition and response to treatment. However, general guidelines include:

• Primary Biliary Cirrhosis: The typical dose ranges from 13-15 mg/kg/day, divided into multiple doses. The sustained-release formulation allows for once or twice daily dosing.
• Liver Disease Management: Dosage may vary, but it is often in the range of 10-15 mg/kg/day, adjusted based on liver function tests and clinical response.

Administration

The sustained-release formulation ensures a gradual release of the medication, providing consistent therapeutic levels over an extended period.

Side Effects

 Common side effects include:

• Gastrointestinal Disturbances: Nausea, diarrhea, and abdominal pain are the most commonly reported side effects.
• Allergic Reactions: Rash, itching, and other allergic reactions may occur in some patients.
• Liver Function Abnormalities: Rarely, there may be a transient increase in liver enzymes, which usually normalizes with continued treatment.

Serious side effects are uncommon but require immediate medical attention. These include:

• Severe Abdominal Pain: Persistent or severe abdominal pain may indicate gallstone complications or other serious conditions.
• Jaundice: Yellowing of the skin or eyes could signal liver dysfunction.

Precautions and Contraindications

Before starting UDCHOLIC SR 450, patients should inform their healthcare provider about any pre-existing conditions, medications, or allergies. Key precautions include:

• Liver Disease: Patients with severe liver disease should use UDCHOLIC SR 450 under strict medical supervision.
• Gallbladder Function: The medication is not recommended for patients with a non-functional gallbladder or certain types of gallstones that do not dissolve with UDCA.

Interactions

UDCHOLIC SR 450 can interact with other medications, which may affect its efficacy or increase the risk of side effects. Notable interactions include:

• Cholestyramine and Colestipol: These medications can reduce the absorption of UDCA, diminishing its effectiveness.
• Estrogen and Oral Contraceptives: These can increase cholesterol levels in bile, potentially counteracting the effects of UDCA.

Patients should always inform their healthcare provider about all medications and supplements they are taking to avoid potential interactions.

Price

 On average, a month's supply of UDCHOLIC SR 450 may range from INR 800 to INR 1500 in India. It is advisable to check with local pharmacies or online retailers for the most accurate pricing.

Conclusion

UDCHOLIC SR 450 is a valuable medication for managing various liver and gallbladder conditions. Its sustained-release formulation offers the convenience of once or twice-daily dosing, improving patient compliance. While generally well-tolerated, patients should be aware of potential side effects and interactions. Regular monitoring by a healthcare professional ensures safe and effective use of UDCHOLIC SR 450, contributing to improved liver health and overall well-being. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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