Vildagliptin 100 mg

Introduction

VILDIABATE 100 is a pharmaceutical formulation containing Vildagliptin (100 mg), a potent dipeptidyl peptidase-4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus (T2DM). This medication helps regulate blood sugar levels by enhancing the action of incretin hormones, which play a vital role in insulin secretion and glucagon suppression. VILDIABATE 100 is widely prescribed to patients who require improved glycemic control when diet and exercise alone are insufficient.

Key Ingredients

• Vildagliptin (100 mg) – A selective DPP-4 inhibitor that enhances endogenous incretin activity, resulting in improved insulin secretion and reduced hepatic glucose production.

How Does VILDIABATE 100 Work?

Vildagliptin acts by inhibiting the DPP-4 enzyme, which degrades incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones are essential for glucose homeostasis as they:

1. Increase Insulin Secretion – In response to glucose intake, incretins stimulate pancreatic beta cells to release insulin.

2. Reduce Glucagon Levels – Incretins suppress the secretion of glucagon from pancreatic alpha cells, thereby preventing excessive glucose production by the liver.

3. Improve Beta-Cell Function – Long-term use of Vildagliptin supports pancreatic beta-cell health, thereby enhancing insulin secretion capacity.

4. Delay Gastric Emptying – Incretins contribute to delayed gastric emptying, promoting better glucose absorption and reducing postprandial spikes.

Uses of VILDIABATE 100

VILDIABATE 100 is primarily indicated for:

• Type 2 Diabetes Mellitus (T2DM) – To achieve better glycemic control when diet and exercise alone are inadequate.

• Monotherapy or Combination Therapy – It can be used as a monotherapy or in combination with other antidiabetic agents such as metformin, sulfonylureas, or thiazolidinediones.

• Prevention of Diabetic Complications – Helps prevent diabetes-related complications like neuropathy, nephropathy, and cardiovascular risks.

Dosage and Administration

The recommended dose of VILDIABATE 100 varies depending on the patient's condition and physician's prescription. General dosage guidelines include:

• Monotherapy: 100 mg once daily or 50 mg twice daily (morning and evening).

• Combination Therapy: When combined with metformin or other antidiabetics, the dose may vary based on the individual's response.

• Renal Impairment: In patients with moderate to severe kidney disease, a lower dose is recommended to prevent drug accumulation.

• Elderly Patients: Dose adjustments may be required for elderly patients to avoid adverse effects.

Important Notes:

• Take the medication at the same time every day.

• Can be taken with or without food.

• Do not exceed the prescribed dose without medical supervision.

Benefits of VILDIABATE 100

• Enhanced Glycemic Control – Effectively lowers both fasting blood sugar (FBS) and postprandial blood sugar (PPBS) levels.

• Beta-Cell Protection – Helps preserve pancreatic beta-cell function over time.

• Low Risk of Hypoglycemia – Unlike sulfonylureas, Vildagliptin does not excessively stimulate insulin, reducing hypoglycemia risk.

• Weight Neutral – Unlike some antidiabetic drugs, Vildagliptin does not cause significant weight gain.

• Well-Tolerated – Minimal side effects compared to other oral hypoglycemic agents.

Side Effects of VILDIABATE 100

Though well-tolerated, VILDIABATE 100 may cause some mild to moderate side effects, including:

Common Side Effects:

• Headache

• Dizziness

• Nausea

• Fatigue

• Mild gastrointestinal discomfort

Less Common but Serious Side Effects:

• Hypoglycemia (when used with other diabetes medications)

• Liver Dysfunction – Rare but possible elevation of liver enzymes; liver function tests are advised during therapy.

• Pancreatitis – Rare cases of acute pancreatitis have been reported; discontinue use if severe abdominal pain occurs.

• Allergic Reactions – Rash, itching, or swelling in rare cases.

Precautions:

• Patients with a history of pancreatitis, liver disease, or renal impairment should consult their doctor before using VILDIABATE 100.

• Regular monitoring of blood sugar levels and kidney/liver function tests is recommended.

• Avoid alcohol consumption as it can increase the risk of liver toxicity and worsen diabetes control.

Drug Interactions

Certain medications may interact with VILDIABATE 100, affecting its efficacy or increasing side effects. Some notable interactions include:

• Metformin – Often used together for enhanced glycemic control.

• Sulfonylureas (e.g., Glimepiride, Gliclazide) – Increased risk of hypoglycemia.

• Insulin – May enhance insulin sensitivity but requires dose adjustments.

• Corticosteroids – May increase blood sugar levels, reducing Vildagliptin's effectiveness.

• ACE Inhibitors (e.g., Enalapril, Lisinopril) – Increased risk of angioedema.

Always inform your healthcare provider about any ongoing medications or supplements before starting VILDIABATE 100.

Who Should Avoid VILDIABATE 100?

• Patients with Type 1 Diabetes Mellitus (T1DM) or Diabetic Ketoacidosis (DKA).

• Individuals with severe kidney or liver disease.

• Pregnant or breastfeeding women (unless prescribed by a doctor).

• Patients with a known allergy to Vildagliptin.

Storage Instructions

• Store at room temperature (15-30°C).

• Keep away from moisture, direct sunlight, and heat.

• Store in a cool, dry place and keep the bottle tightly closed.

• Keep out of reach of children and pets.

Price and Availability in India

The Vildagliptin 100 mg price may vary based on brand, manufacturer, and location. On average, it is available at ₹XX-XX per strip of 10 tablets in pharmacies across India. It is also available in online pharmacies and medical stores.

Conclusion

VILDIABATE 100 (Vildagliptin 100 mg) is an effective and well-tolerated medication for managing type 2 diabetes mellitus (T2DM). Its mechanism of action, safety profile, and low risk of hypoglycemia make it a preferred choice for many diabetic patients. However, it should be taken only under medical supervision, along with a balanced diet and regular exercise for optimal results. If you experience any unusual symptoms while using VILDIABATE 100, consult your healthcare provider immediately.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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