Dapagliflozin and metformin Sustained Release

Introduction

GLIDAPAFLOZIN M 5/500 is an effective oral antidiabetic medication that combines two powerful active ingredients – Dapagliflozin (5mg) and Metformin (500mg). This combination is widely prescribed for managing Type 2 Diabetes Mellitus (T2DM) by improving glycemic control, enhancing insulin sensitivity, and reducing blood glucose levels. Dapagliflozin is a Sodium-Glucose Co-Transporter-2 (SGLT2) inhibitor, while Metformin is a biguanide that reduces hepatic glucose production. Together, they help maintain stable blood sugar levels and reduce the risk of diabetes-related complications.

Key Ingredients

Dapagliflozin (5mg)

• SGLT2 inhibitor that prevents glucose reabsorption in the kidneys.

• Promotes glucose excretion through urine, reducing blood sugar levels.

• Aids in weight management and improves cardiovascular health.

Metformin (500mg)

• Biguanide class drug that decreases glucose production in the liver.

• Enhances insulin sensitivity, improving glucose uptake by muscles.

• Reduces intestinal glucose absorption, preventing post-meal spikes.

Key Benefits

• Effective blood sugar control for Type 2 Diabetes.

• Dual-action mechanism reduces both fasting and postprandial glucose levels.

• Supports weight loss and reduces obesity-related complications.

• Protects cardiovascular health, lowering the risk of heart disease.

• Lowers HbA1c levels, improving long-term diabetes management.

• Enhances insulin sensitivity, reducing insulin resistance.

• Reduces risk of hypoglycemia, as it works independently of insulin secretion.

How Does It Work?

Dapagliflozin and Metformin work together to control diabetes effectively:

1. Dapagliflozin blocks SGLT2 receptors in the kidneys, preventing glucose reabsorption and promoting its excretion through urine.

2. Metformin inhibits glucose production in the liver, reducing excess sugar release into the bloodstream.

3. Together, they lower blood sugar levels, improve insulin efficiency, and promote metabolic health.

Dosage and Directions for Use

• Dosage: The usual recommended dose is one tablet daily, taken with food to minimize stomach discomfort.

• Administration: Swallow the tablet whole with water. Do not crush or chew.

• Doctor’s Advice: Always follow your physician’s prescription for the correct dosage and duration.

• Missed Dose: If a dose is missed, take it as soon as remembered. However, if it's close to the next dose, skip the missed dose and continue as scheduled.

Side Effects of Dapagliflozin (5mg) and Metformin (500mg)

While GLIDAPAFLOZIN M 5/500 is generally well-tolerated, some patients may experience mild to moderate side effects, including:

• Common Side Effects:

  • Nausea

  • Diarrhea

  • Frequent urination

  • Fatigue

  • Hypoglycemia (low blood sugar) when combined with other antidiabetic drugs

• Serious Side Effects:

  • Lactic Acidosis (rare but serious)

  • Dehydration due to excess urination

  • Urinary tract infections (UTIs)

  • Low blood pressure

  • Increased risk of genital infections

Seek immediate medical attention if you experience severe dizziness, muscle pain, difficulty breathing, or unusual fatigue.

Precautions and Warnings

• Not recommended for Type 1 Diabetes or Diabetic Ketoacidosis.

• Avoid in patients with severe kidney disease or liver impairment.

• Pregnant or breastfeeding women should consult a doctor before use.

• Stay hydrated to prevent dehydration due to increased urination.

• Regular kidney function tests are advised during treatment.

Dapagliflozin (5mg) and Metformin (500mg) Price

The price of GLIDAPAFLOZIN M 5/500 varies based on brand, manufacturer, and location. It is generally available in a price range of ₹300 – ₹700 per strip of 10 tablets. Discounts may be available at local pharmacies and online medical stores. Always purchase from a trusted source to ensure authenticity.

Conclusion

GLIDAPAFLOZIN M 5/500 is an advanced oral diabetes medication that provides dual-action glycemic control with Dapagliflozin (5mg) and Metformin (500mg). It helps lower blood sugar levels, improves insulin efficiency, supports weight loss, and protects cardiovascular health. For effective diabetes management, always follow your doctor’s advice and maintain a healthy lifestyle with proper diet and exercise. Consult a healthcare professional before starting this medication for personalized guidance.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW