DX PHYLLIN 400 : Uses, Dosage, Side Effects …

DX PHYLLIN 400

Doxofylline (400mg)

DX PHYLLIN 400, is a medication used primarily for the management of respiratory conditions. It belongs to a class of drugs known as xanthines and is structurally similar to theophylline but with distinct advantages. This article explores the various aspects of Doxofylline (400mg), its uses, benefits, dosage, side effects, and more.

Introduction to Doxofylline (400mg)

 It is commonly prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Unlike theophylline, Doxofylline has a more favorable side effect profile and fewer drug interactions, making it a preferred choice in many clinical settings.

Mechanism of Action

The exact mechanism of action of Doxofylline involves phosphodiesterase inhibition, which leads to bronchodilation and anti-inflammatory effects. It also improves mucociliary clearance, reducing mucus production and enhancing airway function. This dual action makes it effective in managing both acute exacerbations and chronic symptoms of respiratory diseases.

Uses of Doxofylline (400mg)

1. Asthma Management: Doxofylline is used as a maintenance treatment to control symptoms and prevent asthma attacks.

2. COPD: It helps in relieving symptoms of COPD, such as breathlessness and wheezing.

3. Bronchitis: Doxofylline can be prescribed for chronic bronchitis to reduce inflammation and improve airflow.

4. Other Respiratory Conditions: It may also be used in other respiratory disorders where bronchodilation is beneficial.

Benefits of Doxofylline (400mg)

• Improved Tolerability: Compared to older xanthines like theophylline, Doxofylline is better tolerated with fewer side effects like nausea and palpitations.

• Stable Plasma Levels: It has a more predictable pharmacokinetic profile, reducing the need for frequent monitoring compared to theophylline.

• Longer Half-Life: The extended half-life of Doxofylline allows for twice-daily dosing, promoting better patient compliance.

Dosage and Administration

The typical dosage of DX PHYLLIN 400 (Doxofylline 400mg) varies depending on the patient's age, condition severity, and response to treatment.  The dosage should be adjusted based on renal function and any concomitant medications to avoid interactions.

Side Effects

While generally well-tolerated, Doxofylline may cause some side effects, including:

• Gastrointestinal: Nausea, vomiting, abdominal discomfort.

• Central Nervous System: Headache, dizziness.

• Cardiovascular: Palpitations, tachycardia (rapid heart rate).

• Others: Hypersensitivity reactions in rare cases.

Patients should be monitored for these side effects, and dosage adjustments may be necessary to minimize discomfort.

Precautions and Considerations

• Pregnancy and Lactation: Use of Doxofylline during pregnancy or breastfeeding should be carefully considered based on risk-benefit assessment.

• Renal Impairment: Dosage adjustments are required in patients with impaired renal function to prevent drug accumulation.

• Drug Interactions: Doxofylline may interact with certain medications, including antibiotics and antifungals. Always inform healthcare providers about all medications being taken.

Conclusion

Doxofylline (400mg), marketed as DX PHYLLIN 400, is a valuable bronchodilator used in the management of asthma, COPD, and other respiratory conditions. Its unique pharmacological profile offers benefits such as improved tolerability and stable plasma levels, enhancing its utility in clinical practice. However, like all medications, it requires careful dosing and monitoring to ensure efficacy and safety. Patients should follow prescribed guidelines and report any adverse effects promptly to healthcare providers for appropriate management. In conclusion, DX PHYLLIN 400 remains a cornerstone in respiratory care, providing relief and improved quality of life for patients suffering from chronic respiratory ailments. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

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