GLICLAGLAZE MET: USES, PRICE AND ALL DETAILS..

GLICLAGLAZE MET

gliclazide SR (60mg),Metformin SR (500 mg)

GLICLAGLAZE MET is a combination medication containing Gliclazide SR (60 mg) and Metformin SR (500 mg). This extended-release formulation is designed for the effective management of type 2 diabetes mellitus, helping to maintain stable blood sugar levels throughout the day.

Uses
Type 2 Diabetes Mellitus: GLICLAGLAZE MET is prescribed to help lower and control blood sugar levels in adults with type 2 diabetes. It is particularly useful when lifestyle modifications and single-drug therapy are not sufficient.
Mechanism of Action
Gliclazide SR (Sustained Release): A sulfonylurea that stimulates insulin secretion from the pancreatic beta cells. It works by closing ATP-sensitive potassium channels on the beta-cell membrane, leading to depolarization and calcium influx, which triggers insulin release. The sustained-release formulation ensures a prolonged effect, maintaining insulin levels throughout the day.
Metformin SR (Sustained Release): A biguanide that reduces hepatic glucose production, decreases intestinal absorption of glucose, and enhances insulin sensitivity by increasing peripheral glucose uptake and utilization. The sustained-release formulation provides a gradual release, minimizing gastrointestinal side effects and maintaining stable blood glucose levels.
Dosage
Typical Dose: One tablet of GLICLAGLAZE MET taken once or twice daily with meals. The dosage should be individualized based on the patient's current regimen, effectiveness, and tolerance.
Side Effects
Common: Gastrointestinal symptoms such as nausea, vomiting, diarrhea, abdominal pain, and a metallic taste. 
Serious: Lactic acidosis (rare but serious condition related to Metformin), severe hypoglycemia, liver dysfunction, and hematological changes.
Contraindications
Severe renal or hepatic impairment.
Known hypersensitivity to Gliclazide, Metformin, or any other component of the formulation.
Interactions
Medications: Beta-blockers, corticosteroids, diuretics, ACE inhibitors, and other medications that may affect blood glucose levels.
Alcohol: Increases the risk of lactic acidosis and hypoglycemia.
Monitoring
Blood Glucose Levels: Regular monitoring to ensure effective blood glucose control.
Renal Function: Periodic assessment, especially in elderly patients or those with pre-existing renal conditions.
Liver Function: Regular tests to detect any hepatic abnormalities.
Benefits
Effective Glycemic Control: The combination of Gliclazide and Metformin offers a dual mechanism to better manage blood sugar levels.
Convenience: The sustained-release formulations of both medications provide prolonged action, reducing the frequency of dosing and potentially improving patient adherence.
Price
The cost of GLICLAGLAZE MET can vary depending on the manufacturer and the pharmacy. Patients should check with their local pharmacies for specific pricing.
Conclusion
GLICLAGLAZE MET is a potent combination therapy for managing type 2 diabetes mellitus. By combining the sustained-release formulations of Gliclazide and Metformin, it provides comprehensive blood glucose control throughout the day, crucial for preventing diabetes-related complications.Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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