Empagliflozin (5mg) & Metformin Hydrochloride (1000mg): A Powerful Duo for Managing Type 2 Diabetes

Feb 05, 2025

Introduction

GLIEMPAFLOZIN MET 5mg/1000mg is a powerful combination of two essential antidiabetic agents, Empagliflozin (5mg) and Metformin Hydrochloride (1000mg), designed to effectively manage Type 2 Diabetes Mellitus (T2DM). This dual-action medication helps regulate blood sugar levels, enhances insulin sensitivity, and promotes overall metabolic health.

Millions of people worldwide struggle with Type 2 Diabetes, and finding the right medication can be challenging. GLIEMPAFLOZIN MET 5mg/1000mg provides an optimized solution, working through both renal glucose excretion and glucose metabolism regulation to achieve superior glycemic control.

Key Ingredients

Empagliflozin (5mg)

Empagliflozin is a selective Sodium-Glucose Co-Transporter-2 (SGLT2) inhibitor, which helps lower blood glucose levels by increasing urinary glucose excretion. It also provides additional benefits such as weight loss and cardiovascular protection. Key functions include:

  • Reducing glucose reabsorption in the kidneys

  • Enhancing glucose excretion through urine

  • Decreasing blood sugar levels without causing excessive insulin secretion

Metformin Hydrochloride (1000mg)

Metformin Hydrochloride belongs to the biguanide class of drugs and is a first-line treatment for Type 2 Diabetes Mellitus. It improves insulin sensitivity, reduces glucose production in the liver, and helps in better glucose utilization by the muscles. Key functions include:

  • Suppressing hepatic glucose production

  • Enhancing insulin sensitivity

  • Lowering intestinal glucose absorption

  • Promoting weight management and metabolic health

How GLIEMPAFLOZIN MET 5mg/1000mg Works

The dual-action approach of GLIEMPAFLOZIN MET 5mg/1000mg provides multiple benefits for patients with Type 2 Diabetes Mellitus:

  1. Reduction in Blood Glucose LevelsEmpagliflozin (5mg) eliminates excess glucose via urine, while Metformin Hydrochloride (1000mg) suppresses glucose production in the liver.

  2. Weight Management – The SGLT2 inhibition mechanism promotes weight loss by reducing glucose absorption and increasing energy expenditure.

  3. Cardiovascular BenefitsEmpagliflozin (5mg) has shown cardiovascular protective effects, reducing the risk of heart failure and cardiovascular-related mortality.

  4. Insulin Sensitivity EnhancementMetformin Hydrochloride (1000mg) improves the body's response to insulin, lowering insulin resistance.

  5. Reduction of HbA1c Levels – Clinical studies show that the combination effectively reduces HbA1c levels over time.

Uses of GLIEMPAFLOZIN MET 5mg/1000mg

  • Management of Type 2 Diabetes Mellitus

  • Reduction in blood glucose levels

  • Cardiovascular protection in diabetic patients

  • Prevention of diabetic complications like neuropathy, nephropathy, and retinopathy

  • Weight control in diabetic individuals

Dosage & Administration

GLIEMPAFLOZIN MET 5mg/1000mg should be taken as prescribed by a healthcare provider. General recommendations include:

  • Standard Dose: One tablet per day, preferably with food.

  • Titration: The dose may be adjusted based on individual glucose levels and tolerability.

  • Missed Dose: If a dose is missed, take it as soon as possible. If it is close to the next scheduled dose, skip the missed dose—do not double up.

Potential Side Effects

While GLIEMPAFLOZIN MET 5mg/1000mg is well-tolerated, some individuals may experience side effects, including:

  • Common Side Effects:

    • Increased urination

    • Mild nausea

    • Abdominal discomfort

    • Loss of appetite

    • Dizziness

    • Mild diarrhea

  • Serious Side Effects (Rare):

    • Ketoacidosis – Seek medical help if you experience nausea, vomiting, or difficulty breathing.

    • Lactic Acidosis – Symptoms include muscle pain, extreme weakness, and irregular heartbeat.

    • Hypoglycemia (Low Blood Sugar) – More common when used with insulin or sulfonylureas.

Precautions & Warnings

  • Not recommended for individuals with severe kidney disease or end-stage renal disease.

  • Avoid in Type 1 Diabetes or diabetic ketoacidosis.

  • Patients with a history of lactic acidosis, heart failure, or severe liver disease should consult their doctor before use.

  • Not recommended during pregnancy or breastfeeding unless prescribed by a doctor.

Drug Interactions

GLIEMPAFLOZIN MET 5mg/1000mg may interact with other medications, such as:

  • Diuretics – May increase the risk of dehydration and hypotension.

  • Insulin & Sulfonylureas – Can cause hypoglycemia.

  • ACE Inhibitors & ARBs – May enhance glucose-lowering effects.

  • Beta-blockers – Can mask symptoms of hypoglycemia.

Price & Availability in India

The price of Empagliflozin (5mg), Metformin Hydrochloride (1000mg) varies by brand and pharmacy location. On average, a monthly supply may cost ₹800 to ₹1500, depending on manufacturer discounts and availability.

Conclusion

GLIEMPAFLOZIN MET 5mg/1000mg is a cutting-edge combination therapy for Type 2 Diabetes Mellitus, offering superior glycemic control, cardiovascular protection, weight management, and improved insulin sensitivity. By integrating Empagliflozin (5mg) and Metformin Hydrochloride (1000mg), this medication provides an effective and well-rounded approach to diabetes care. For optimal results, always follow medical advice, maintain a healthy diet, engage in regular physical activity, and monitor blood glucose levels consistently. If you experience any side effects or have concerns about interactions with other medications, consult your healthcare provider immediately.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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