GLIMITERIS TRIO 0.2 : Tablet - Steris Healthcare PVT LTD………

May 23, 2024

Voglibose 0.2 mg, Glimepiride 3 mg & Metformin Hydrochloride 500 mg & GLIMITERIS TRIO 0.2

Voglibose 0.2 mg, Glimepiride 3 mg, and Metformin Hydrochloride 500 mg is a combination medication commonly used to manage type 2 diabetes. This article explores its uses, side effects, dosage, and mechanisms of action, providing comprehensive information for patients and healthcare providers.

Uses

This combination medication is primarily prescribed for:

  • Type 2 Diabetes Management: It is used to improve glycemic control in patients with type 2 diabetes, particularly those who do not achieve adequate control with diet, exercise, and monotherapy.
  • Improving Insulin Sensitivity: Helps enhance the body's response to insulin, thereby improving blood sugar levels.
  • Preventing Complications: Aims to prevent long-term complications of diabetes such as cardiovascular diseases, neuropathy, nephropathy, and retinopathy.

Side Effects

Common side effects of this combination medication may include:

  • Gastrointestinal Issues: Nausea, vomiting, diarrhea, abdominal pain, and flatulence are common, particularly with metformin.
  • Hypoglycemia: Glimepiride can cause low blood sugar levels, leading to symptoms like dizziness, sweating, and confusion.
  • Weight Gain: Some patients may experience weight gain due to glimepiride.
  • Skin Reactions: Voglibose can cause skin reactions such as rash or itching.
  • Metallic Taste: Metformin may cause a metallic taste in the mouth.

Severe side effects are rare but can include severe hypoglycemia, lactic acidosis (a rare but serious side effect of metformin), and severe allergic reactions. Immediate medical attention is required if these occur.

Dosage

The dosage of Voglibose 0.2 mg, Glimepiride 3 mg, and Metformin Hydrochloride 500 mg varies based on individual patient needs and response to treatment. General guidelines include:

  • Starting Dose: Typically, one tablet is taken once or twice daily with meals.
  • Adjustment: The dosage can be adjusted by the healthcare provider based on the patient's blood sugar levels and tolerance to the medication.

Patients should follow the prescribed dosage and not exceed the recommended amount without consulting a healthcare provider. It is important to take the medication with food to reduce gastrointestinal side effects.

Mechanism of Action

This combination medication works through the individual actions of its components:

  • Voglibose: Inhibits alpha-glucosidase enzymes in the intestine, delaying the digestion and absorption of carbohydrates, leading to a slower and lower rise in blood glucose levels after meals.
  • Glimepiride: Stimulates the pancreas to release more insulin by increasing the responsiveness of pancreatic beta cells to glucose, thereby reducing blood sugar levels.
  • Metformin: Decreases hepatic glucose production, improves insulin sensitivity, and increases peripheral glucose uptake and utilization, resulting in better blood sugar control.

Conclusion

Voglibose 0.2 mg, Glimepiride 3 mg, and Metformin Hydrochloride 500 mg is an effective combination medication for managing type 2 diabetes. Understanding its uses, potential side effects, proper dosage, and mechanisms of action can help ensure safe and effective treatment. For personalized advice and optimal results, consulting with healthcare professionals is recommended. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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