Sacubitril (97mg), Valsartan (103mg) ...............l
Dec 06, 2023
Sacubitril (97mg), Valsartan (103mg)
SACUBRIGHT 200
Sacubitril/valsartan is a combination medication used in the treatment of heart failure. It combines two active ingredients, sacubitril and valsartan, and is commonly prescribed under the brand name Entresto. Neprilysin inhibitor
Mechanism of Action: Sacubitril inhibits neprilysin, an enzyme that breaks down natural substances in the body that help dilate blood vessels and reduce sodium retention. Inhibition of neprilysin increases the levels of these substances, promoting vasodilation and diuresis.Sacubitril is used in combination with valsartan for the treatment of heart failure with reduced ejection fraction (HFrEF).Angiotensin II receptor blocker (ARB)
Mechanism of Action: Valsartan blocks the action of angiotensin II, a hormone that narrows blood vessels and increases blood pressure. By blocking angiotensin II receptors, valsartan relaxes blood vessels, reduces blood pressure, and decreases the workload on the heart.
Indications: Valsartan is used to treat hypertension (high blood pressure) and is also used in combination with sacubitril for the treatment of HFrEF.
Synergistic Effect: The combination of sacubitril and valsartan provides a synergistic effect by addressing different pathways involved in heart failure. It helps improve symptoms, reduce hospitalizations, and increase survival rates in patients with HFrEF.
Angiotensin Receptor Neprilysin Inhibitor (ARNI): The combination is classified as an ARNI, reflecting its dual mechanism of action.Steris Healthcare Pvt. Ltd. is a Leading Pharmaceutical Company in India. Established in the year of May 2018. We have 750+ Products & 16+ Super Specialty Segments. Every week we have a new product in our portfolio. In Last 5 years we are dealing in Chronic Therapy and in 5 years we grow by 200% Annually, because we deal in high quality medicine. Steris medicine manufactures at WHO-GMP Approved Plants & We have Legal manufacturing contracts with all leading manufacturers of India. Today we have 1000+ Business Franchise Partners in PAN India. Steris's medicine supply in India's Top or Reputed Hospitals, Pharmacy, Government use or Railway use. Grow with a similar pace with the STERIS. Be first to launch like us.
For further information please contact:
info@sterispharma.com
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https://www.sterisonline.com/product/sacubright-200-134307
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