Sulfasalazine 1000 mg Tablet: View Uses, Dosage, Benefits, Side Effects.

Sulfasalazine 1000 mg is a powerful anti-inflammatory and immunomodulatory medication commonly prescribed to treat chronic inflammatory conditions such as rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is widely used due to its dual action, targeting both the immune response and inflammation. Available in the form of oral tablets, sulfasalazine 1000 mg tablet has become a staple in the treatment plans of patients requiring long-term disease management.

In this article, we'll explore the uses, dosage, benefits, potential side effects, and pricing,  Sulfasalazine is used to treat ulcerative colitis.. We'll also delve into how this medicine works, who should use it, and where you can purchase it. 

What is Sulfasalazine 1000 mg?

Sulfasalazine 1000 mg is a disease-modifying antirheumatic drug (DMARD) and belongs to the class of sulfa drugs. It is a combination of sulfapyridine and 5-aminosalicylic acid (5-ASA), which work synergistically to reduce inflammation and suppress abnormal immune system activity.

It is available as a tablet for oral administration and is usually taken in divided doses throughout the day.

Sulfasalazine 1000 mg Uses

Tab Sulfasalazine 1000 mg is primarily used for treating the following conditions:

1. Rheumatoid Arthritis

Sulfasalazine is widely prescribed to manage rheumatoid arthritis, an autoimmune disease that causes chronic joint inflammation. It helps in reducing pain, swelling, and stiffness in the joints.

2. Ulcerative Colitis

It is effective in treating ulcerative colitis, an inflammatory bowel disease that affects the colon and rectum. Sulfasalazine helps in inducing and maintaining remission.

3. Crohn's Disease

Though not the first-line treatment, sulfasalazine 1000 mg is sometimes used in managing Crohn's disease, particularly when the colon is involved.

4. Ankylosing Spondylitis

Sulfasalazine 1000 mg may be prescribed in ankylosing spondylitis, especially when peripheral joints are affected.

5. Juvenile Idiopathic Arthritis

In pediatric populations, sulfasalazine is occasionally used for juvenile idiopathic arthritis, although under strict medical supervision.  

Available Substitute In Sulfasalazine: Steris Healthcare Pvt ltd.

Steris Healthcare Pvt Ltd offers a reliable and effective substitute in the Sulfasalazine category with its product SULFASALAZ 500 15’s. Designed to meet the therapeutic needs of patients with inflammatory bowel conditions like ulcerative colitis and rheumatoid arthritis, SULFASALAZ 500 contains Sulfasalazine 500 mg per tablet and is formulated for consistent performance and patient safety.

As a trusted pharmaceutical manufacturer, Steris Healthcare ensures that SULFASALAZ 500 15’s is produced in WHO-GMP certified facilities, maintaining high standards of quality, purity, and efficacy. This substitute provides healthcare professionals with a dependable alternative for Sulfasalazine therapy at an affordable price point, ensuring better accessibility and patient adherence. 

How Sulfasalazine 1000 mg Works

Sulfasalazine is broken down in the colon into sulfapyridine and 5-ASA. While 5-ASA has anti-inflammatory effects on the lining of the bowel, sulfapyridine is absorbed into the bloodstream and modulates the immune system. Together, they help suppress inflammation and manage autoimmune responses effectively.

Dosage and Administration

The dosage of Sulfasalazine 1000 mg Tablet depends on the condition being treated, age, and the patient's response to the drug.

For Adults:

• Ulcerative Colitis: 2 to 4 grams per day in divided doses.

• Rheumatoid Arthritis: Start with 500 mg to 1 gram daily, gradually increasing to 2 to 3 grams per day in divided doses.

For Children:

• Dosage is typically based on body weight and must be determined by a pediatric specialist.

Administration Tips:

• Take with food to reduce gastrointestinal upset.

• Ensure adequate fluid intake.

• Do not crush or chew the tablet; swallow it whole.

Benefits of Sulfasalazine 1000 mg Tablet

• Reduces joint pain and stiffness in arthritis patients

• Promotes healing of the intestinal lining in ulcerative colitis

• Delays disease progression in autoimmune conditions

• Improves quality of life in chronic inflammatory disorders

• Cost-effective treatment compared to some biologics and newer drugs 

Side Effects of Sulfasalazine 1000 mg

Like any medication, Sulfasalazine 1000 mg tablet may cause side effects. Most are mild and can be managed, but some may require medical attention.

• Nausea

• Headache

• Loss of appetite

• Skin rash

• Vomiting

• Abdominal discomfort

Serious Side Effects:

• Blood disorders (low white or red blood cell count)

• Liver dysfunction

• Severe skin reactions

• Hypersensitivity reactions

• Fertility issues in men (usually reversible)

Patients should have regular blood tests to monitor blood counts and liver function.

Who Should Avoid Sulfasalazine?

• People allergic to sulfa drugs

• Patients with liver or kidney impairment

• Those with blood dyscrasias

• Pregnant or breastfeeding women (unless advised by a doctor)

Drug Interactions

Sulfasalazine may interact with:

• Digoxin

• Warfarin

• Methotrexate

• Folic acid (may need supplementation)

• Oral hypoglycemic drugs

Always inform your doctor about all medicines and supplements you are taking.

Storage and Handling

• Store at room temperature (15-30°C)

• Protect from moisture and light

• Keep out of reach of children 

Sulfasalazine 1000 mg Price in Steris Healthcare

The sulfasalazine 1000 mg price can vary based on the brand and pharmacy. On average, the cost per strip ranges between ₹183.40 to ₹183.40. A month’s supply (60 tablets) may cost a Box between ₹1840 to ₹2000.

You can purchase tab sulfasalazine 1000 mg from:

• Local pharmacies

• Online platforms like 1mg, Netmeds, Apollo, and SastaSundar

• Directly from hospital pharmacies

Popular Brands of Sulfasalazine 1000 mg in India

• Sazo 1000 mg by Wallace Pharmaceuticals

• Zydus Sulfa 1000 mg

• Sulfasal by Intas

• Sulcol by Cipla

Always opt for a reputed brand and consult your physician for brand recommendations. 

Why Steris Healthcare is the best For Sulfasalazine 1000 mg Tablet?

Steris Healthcare stands out as a trusted and reliable pharmaceutical company when it comes to providing high-quality Sulfasalazine 1000 mg Tablets. With a commitment to excellence, Steris Healthcare ensures that each tablet is manufactured under stringent quality standards in WHO-GMP-certified facilities, ensuring safety, efficacy, and consistency. The company prioritizes patient well-being by offering clinically validated formulations that comply with both national and international regulatory norms. Steris Healthcare also emphasizes affordability without compromising on quality, making tab Sulfasalazine 1000 mg accessible to a wider population. Moreover, its robust supply chain and responsive customer support make it a preferred choice among healthcare professionals and distributors across India.